Gene Symbol | RASSF10 |
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Entrez Gene | 644943 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 |
Other Description | ras association domain-containing protein 10 |
Swissprots | A6NK89 |
Accessions | A6NK89 BX098487 NM_001080521 NP_001073990 |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:20956940}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20956940}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20956940}. Note=During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase. Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm. |
Tissue Specificity | Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70% WHO grade IV primary glioblastomas, but not in grade I astrocytomas. {ECO:0000269|PubMed:20956940}. |
RASSF10 (E-16) - sc-243929 from Santa Cruz Biotechnology
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RASSF10 (S-17) - sc-243928 from Santa Cruz Biotechnology
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Anti-RASSF10 antibody - ab113105 from Abcam
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Anti-RASSF10 antibody - N-terminal - ab189999 from Abcam
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Anti-RASSF10 Antibody (aa230-259, FITC) - LS-C239790 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa230-259, AP) - LS-C239787 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa230-259, Biotin) - LS-C239788 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa230-259, APC) - LS-C239789 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa230-259, PE) - LS-C239792 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa230-259, Azide-free, HRP) - LS-C248621 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa229-259) - LS-C324543 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (aa230-259) - LS-C162463 from LifeSpan Bioscience
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Anti-RASSF10 Antibody (N-Terminus) IHC-plus⢠- LS-B9520 from LifeSpan Bioscience
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RASSF10 Antibody - NBP2-41130 from Novus Biologicals
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Anti-RASSF10 antibody produced in rabbit - SAB3500627 from Sigma-Aldrich
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ANTI-RASSF10 (CENTER) antibody produced in rabbit - SAB1301280 from Sigma-Aldrich
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RASSF10-Antibody-Center - AP12444c from Abgent, a WuXi AppTec company
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RASSF10 Antibody - middle region (OAAB08712) - OAAB08712 from Aviva Systems Biology
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RASSF10 antibody - orb75619 from Biorbyt
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RASSF10 (N-term) antibody - AP26148PU-N from Acris Antibodies
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RASSF10 (Center) antibody - AP53592PU-N from Acris Antibodies
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RASSF10 Antibody - 6371 from ProSci
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RASSF10 Antibody - 254477 from ABBIOTEC
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RASSF10 Antibody - 25313 from Signalway Antibody
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Anti-RASSF10 (N-terminal) polyclonal antibody - DPAB-L20985 from Creative Diagnostics
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