Gene Symbol | RASSF10 |
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Entrez Gene | 644943 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 |
Other Description | ras association domain-containing protein 10 |
Swissprots | A6NK89 |
Accessions | A6NK89 BX098487 NM_001080521 NP_001073990 |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:20956940}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20956940}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20956940}. Note=During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase. Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm. |
Tissue Specificity | Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70% WHO grade IV primary glioblastomas, but not in grade I astrocytomas. {ECO:0000269|PubMed:20956940}. |
RASSF10 Antibody Blocking Peptide - LS-E1679 from LifeSpan Bioscience
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RASSF10 Antibody Blocking Peptide - LS-E31125 from LifeSpan Bioscience
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RASSF10-Antibody-Center-Blocking-peptide - BP12444c from Abgent, a WuXi AppTec company
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RASSF10 control peptide - AP26149CP-N from Acris Antibodies
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RASSF10 Peptide - 6371P from ProSci
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Recombinant Human Ras association domain-containing protein 10(RASSF10) - CSB-YP019373HU CSB-EP019373HU CSB-BP019373HU CSB-MP019373HU from Cusabio
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RASSF10 Peptide, Human - M34GP13010H from Creative Peptides
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Ras association domain-containing protein 10 (RASSF10), Recombinant Protein - MBS1248325 from MyBioSource
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