Gene Symbol | TWISTNB |
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Entrez Gene | 221830 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | TWIST neighbor |
Other Description | DNA-directed RNA polymerase I subunit RPA43|twist neighbor protein |
Swissprots | A0PJ45 B7Z724 Q3B726 |
Accessions | CCQ43008 DAA05732 EAL24277 EAW93714 Q3B726 AK090846 AK301329 BAH13460 BC013179 BC014574 AAH14574 BC056267 BC070358 BC130298 AAI30299 BC130300 AAI30301 HQ258381 ADR83135 NM_001002926 NP_001002926 |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. |
Subcellular Location | Nucleus, nucleolus {ECO:0000250}. |
Tissue Specificity | Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. {ECO:0000269|PubMed:12438708}. |
Top Pathways | Purine metabolism, RNA polymerase, Pyrimidine metabolism |
TWISTNB Antibody Blocking Peptide - LS-E22958 from LifeSpan Bioscience
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TWISTNB fusion protein - Ag18966 from Proteintech Group
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TWISTNB fusion protein - Ag18783 from Proteintech Group
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Recombinant Human TWISTNB, His-tagged - TWISTNB-3495H from Creative Biomart
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Recombinant Human DNA-directed RNA polymerase I subunit RPA43(TWISTNB) - CSB-YP658940HU CSB-EP658940HU CSB-BP658940HU CSB-MP658940HU from Cusabio
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TWISTNB - TP322203 from Acris Antibodies
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TWISTNB Recombinant Protein Antigen - NBP1-89454PEP from Novus Biologicals
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TWISTNB Recombinant Protein Antigen - NBP1-89449PEP from Novus Biologicals
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RPA43-Antibody-C-term-Blocking-Peptide - BP5260b from Abgent, a WuXi AppTec company
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TWISTNB Peptide, Human - M34GP16885H from Creative Peptides
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DNA-directed RNA polymerase I subunit RPA43 (TWISTNB), Recombinant Protein - MBS1347975 from MyBioSource
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