CASR

Gene Symbol CASR
Entrez Gene 846
Alt Symbol CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1
Species Human
Gene Type protein-coding
Description calcium-sensing receptor
Other Description extracellular calcium-sensing receptor|parathyroid Ca(2+)-sensing receptor 1|parathyroid cell calcium-sensing receptor 1
Swissprots Q16379 Q16109 Q4PJ19 Q13912 Q16108 P41180 Q16110 Q2M1T0
Accessions AAB29413 AAB29414 AAB29415 AAP20759 AAY68221 ABD04091 ABD04092 ABD04093 ABD04094 ABD04095 ABD04096 ABK33660 ABK33661 ABK33662 ABK33663 CAA56990 CAV33589 CCV20013 CCW28005 EAW79490 EAW79491 EAW79492 P41180 BC104999 AAI05000 BC112236 AAI12237 BP388878 D50855 BAA09453 FJ360896 ACJ04039 S79217 AAB35262 S81755 AAD14370 S83176 AAB46873 U20759 AAA86503 U20760 AAA86504 W56898 XM_005247836 XP_005247893 XM_005247837 XP_005247894 XM_006713789 XP_006713852 XM_011513237 XP_011511539 XM_011513238 XP_011511540 XM_011513239 XP_011511541 NM_000388 NP_000379 NM_001178065 NP_001171536
Function Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
Subcellular Location Cell membrane {ECO:0000269|PubMed:20861236}; Multi-pass membrane protein {ECO:0000269|PubMed:20861236}.
Tissue Specificity Expressed in the temporal lobe, frontal lobe, parietal lobe, hippocampus, and cerebellum. Also found in kidney, lung, liver, heart, skeletal muscle, placenta. {ECO:0000269|PubMed:18756473}.

CaSR (F-19) - sc-32181 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CaSR (F-19): sc-32181. Western blot analysis of CaSR expression in Caki-1 (A), MDCK (B) and U-2 OS (C) whole cell lysates.

CaSR (A-18) - sc-32182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CaSR (6D4) - sc-47741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CaSR (6D4): sc-47741 Western blot analysis of CaSR expression in rat brain (A) and rat placenta (B) tissue extracts.

CaSR (H-100) - sc-33821 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CaSR (H-100): sc-33821. Western blot analysis of CaSR expression in U-2 OS (A), HeLa (B) and HEK293 (C) whole cell lysates and rat brain tissue extract (D).

CaSR (N-14) - sc-32180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Calcium Sensing Receptor (phospho T888) antibody - ab62214 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells, using ab62214 (1/500 - 1/1000) staining Calcium Sensing Receptor; in the presence and absence of immunizing peptide.

Anti-Calcium Sensing Receptor (phospho T888) antibody - ab182619 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Calcium Sensing Receptor (phospho T888) antibody (ab182619) at 1/500 dilutionLane 1 : LOVO cell extracts with antigen specific peptideLane 2 : LOVO cell extractsSecondaryAnti-rabbit HRP conjugated antibodydeveloped using the ECL technique

Anti-Calcium Sensing Receptor (phospho T888) antibody - ab195711 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Calcium Sensing Receptor (phospho T888) antibody (ab195711) at 1/500 dilutionLane 1 : LOVO whole cell lysate with antigen-specific peptideLane 2 : LOVO whole cell lysate

Anti-Calcium Sensing Receptor antibody - ab62653 from Abcam

Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin embedded human brain tissue using ab62653 at a 1/50 dilution. Left image untreated. Right image treated with peptide.

Anti-Calcium Sensing Receptor antibody - ab18200 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Calcium Sensing Receptor antibody (ab18200) at 1 µg/mlLane 1 : CASR 293T Cell Transient Overexpression Lysate Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate (negative control)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutionPerformed under reducing conditions.Observed band size : 130 kDa (why is the actual band size different from the predicted?)Additional bands at : 200 kDa,50 kDa,80 kDa. We are unsure as to the identity of these extra bands.Exposure time : 3 minutesIn this experiment Hek293 was used as a negative control.

Anti-Calcium Sensing Receptor antibody - ab79038 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue, staining Calcium Sensing Receptor with ab79038 at 5 µg/ml.

Anti-Calcium Sensing Receptor antibody - ab31212 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Calcium Sensing Receptor antibody [HL1499] - ab183355 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone HL1499
Anti-Calcium Sensing Receptor antibody [HL1499] (ab183355) at 1/50 dilution + Transfected 293 cell lysatedeveloped using the ECL technique

Anti-Calcium Sensing Receptor antibody, prediluted - ab27493 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Paraffin embedded formalin fixed human placenta tissue section stained with anti Calcium Sensing Receptor (ab27493).

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus) IHC-plus™ - LS-B12064 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus) IHC-plus™ - LS-A1427 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CASR/Calcium Sensing Receptor antibody IHC of human Parathyroid, Adenoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CASR/Calcium Sensing Receptor Antibody (C-Terminus) - LS-C4297 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CASR/Calcium Sensing Receptor Antibody (C-Terminus) - LS-C4299 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus) IHC-plus™ - LS-A1426 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CASR antibody LS-A1426 IHC of human parathyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CASR/Calcium Sensing Receptor Antibody - LS-C96200 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499, Biotin) - LS-C140884 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499, DY488) - LS-C140886 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499, DY650) - LS-C140885 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499, HRP) - LS-C140887 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499, DY550) - LS-C140888 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
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