ELFN1

Gene Symbol ELFN1
Entrez Gene 392617
Alt Symbol PPP1R28
Species Human
Gene Type protein-coding
Description extracellular leucine-rich repeat and fibronectin type III domain containing 1
Other Description extracellular leucine-rich repeat and fibronectin type III containing 1|extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1|protein ELFN1|protein phosphatase 1 regulatory subunit 28|protein phosphatase 1, regulatory subunit 28
Swissprots P0C7U0 H3BS57
Accessions EAW87217 P0C7U0 AI962473 BF434584 DR001365 XM_006715725 XP_006715788 XM_006715726 XP_006715789 XM_006715727 XP_006715790 XM_011515397 XP_011513699 XM_011515398 XP_011513700 XM_011515399 XP_011513701 XM_011515400 XP_011513702 XM_011515401 XP_011513703 NM_001128636 NP_001122108
Function Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. {ECO:0000250, ECO:0000269|PubMed:19389623}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000250}. Note=Localizes to excitatory synapses onto somatostatin (Sst)-containing oriens-lacunosum moleculare (O-LM) interneurons. {ECO:0000250}.

ELFN1 CRISPR/Cas9 KO Plasmid (h) - sc-405274 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 HDR Plasmid (h) - sc-405274-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 Double Nickase Plasmid (h) - sc-405274-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 Double Nickase Plasmid (h2) - sc-405274-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 CRISPR Activation Plasmid (h) - sc-405274-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 CRISPR Activation Plasmid (h2) - sc-405274-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 Lentiviral Activation Particles (h) - sc-405274-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 Lentiviral Activation Particles (h2) - sc-405274-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELFN1 siRNA (h) - sc-89382 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELFN1 shRNA Plasmid (h) - sc-89382-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELFN1 shRNA (h) Lentiviral Particles - sc-89382-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7804 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7804 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ELFN1 siRNA (Human) - CRJ8047 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELFN1 - MBS8213322 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Elfn1 (NM_001128636.2) - SHH285053 from Creative biogene

Category siRNA
Species Reactivities Human

ELFN1 shRNA Plasmid (Human) - CHJ8047 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ELFN1 miRNA 3'UTR clone - MiUTR3H-14728 from Creative biogene

Species Reactivities Human
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