Gene Symbol | HPRT1 |
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Entrez Gene | 395653 |
Alt Symbol | HPRT |
Species | Chicken |
Gene Type | protein-coding |
Description | hypoxanthine phosphoribosyltransferase 1 |
Other Description | HGPRT|HGPRTase|hypoxanthine guanine phosphoribosyl transferase|hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)|hypoxanthine-guanine phosphoribosyltransferase |
Swissprots | Q9W719 |
Accessions | Q9W719 AJ132697 CAB46657 NM_204848 NP_990179 |
Function | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Purine metabolism, Drug metabolism - other enzymes |
Recombinant Chicken HPRT1 - HPRT1-6411C from Creative Biomart
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Recombinant Chicken Hypoxanthine-guanine phosphoribosyltransferase(HPRT1) - CSB-YP896205CH CSB-EP896205CH CSB-BP896205CH CSB-MP896205CH from Cusabio
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Hypoxanthine-guanine phosphoribosyltransferase (HPRT1), Recombinant Protein - MBS1447236 from MyBioSource
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