| Gene Symbol |
HPRT1
|
| Entrez Gene |
395653
|
| Alt Symbol |
HPRT
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
hypoxanthine phosphoribosyltransferase 1
|
| Other Description |
HGPRT|HGPRTase|hypoxanthine guanine phosphoribosyl transferase|hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)|hypoxanthine-guanine phosphoribosyltransferase
|
| Swissprots |
Q9W719
|
| Accessions |
Q9W719 AJ132697 CAB46657 NM_204848 NP_990179
|
| Function |
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Purine metabolism, Drug metabolism - other enzymes
|