HPRT1

Gene Symbol HPRT1
Entrez Gene 395653
Alt Symbol HPRT
Species Chicken
Gene Type protein-coding
Description hypoxanthine phosphoribosyltransferase 1
Other Description HGPRT|HGPRTase|hypoxanthine guanine phosphoribosyl transferase|hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)|hypoxanthine-guanine phosphoribosyltransferase
Swissprots Q9W719
Accessions Q9W719 AJ132697 CAB46657 NM_204848 NP_990179
Function Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Top Pathways Purine metabolism, Drug metabolism - other enzymes

Anti-HPRT antibody - ab10479 from Abcam

Prices $400.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab10479 stained human HeLa cells. The cells were methanol fixed ( 5 min) and incubated with the antibody (ab10479, 5µg/ml) for 1h at room temperature. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Image-iTTM FX Signal Enhancer was used as the primary blocking agent, 5% BSA (in TBS-T) was used for all other blocking steps. DAPI was used to stain the cell nuclei (blue). Alexa Fluor® 594 phalloidin was used to label F-actin (red).

Anti-HPRT antibody - ab81059 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HPRT antibody (ab81059) at 1 µg/ml (in 5% skim milk / PBS buffer) + HeLa cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution
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