Gene Symbol | NHP2L1 |
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Entrez Gene | 4809 |
Alt Symbol | 15.5K, FA-1, FA1, NHPX, OTK27, SNRNP15-5, SNU13, SPAG12, SSFA1 |
Species | Human |
Gene Type | protein-coding |
Description | NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) |
Other Description | NHP2-like protein 1|U4/U6.U5 tri-snRNP 15.5 kDa protein|[U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein|high mobility group-like nuclear protein 2 homolog 1|non-histone chromosome protein 2-like 1|small nuclear ribonucleoprotein 15.5kDa (U4/U6.U5)|sperm specific antigen 1 |
Swissprots | P55769 |
Accessions | CAH05699 CAR82348 EAW60450 EAW60451 EAW60452 EAW60453 P55769 AF091076 AAC72945 AF155235 AAF06959 AK311800 BAG34743 BC005358 AAH05358 BC019282 AAH19282 BC095439 AAH95439 BG164621 BI770951 CF552526 CR456531 CAG30417 CR541725 CAG46526 CU013131 CAK54562 CU013419 CAK54861 D50420 BAA23363 DB021462 XM_011530201 XP_011528503 NM_001003796 NP_001003796 NM_005008 NP_004999 |
Function | Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. {ECO:0000269|PubMed:10545122, ECO:0000269|PubMed:17412961}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:10593953, ECO:0000269|PubMed:12429849, ECO:0000269|Ref.7}. Note=Concentrated in the dense fibrillar component of the nucleolus. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Spliceosome, Ribosome biogenesis in eukaryotes |
NHPX (FL-128) - sc-366912 from Santa Cruz Biotechnology
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NHPX (L-12) - sc-86759 from Santa Cruz Biotechnology
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NHPX (N-14) - sc-86760 from Santa Cruz Biotechnology
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Anti-NHP2L1 antibody - ab95958 from Abcam
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Anti-NHP2L1 antibody - ab174648 from Abcam
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Anti-NHP2L1 antibody [EPR11671] - ab181982 from Abcam
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Anti-NHP2L1 Antibody (N-Terminus) - LS-C116174 from LifeSpan Bioscience
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Anti-NHP2L1 Antibody (clone 5C5) - LS-C197781 from LifeSpan Bioscience
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Anti-NHP2L1 Antibody (aa71-121) - LS-C290672 from LifeSpan Bioscience
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Anti-NHP2L1 Antibody - LS-C334388 from LifeSpan Bioscience
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Anti-NHP2L1 Antibody (aa1-128) - LS-C186056 from LifeSpan Bioscience
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NHP2L1 Antibody - NBP1-32732 from Novus Biologicals
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NHP2L1 Antibody - NBP1-89406 from Novus Biologicals
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NHP2L1 Antibody - NB120-15873 from Novus Biologicals
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NHP2L1 Antibody - H00004809-A01 from Novus Biologicals
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NHP2L1 Antibody (5C5) - H00004809-M02 from Novus Biologicals
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Anti-NHP2L1 antibody produced in rabbit - HPA029199 from Sigma-Aldrich
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Anti-NHP2L1 antibody produced in rabbit - SAB2702030 from Sigma-Aldrich
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Anti-NHP2L1 antibody produced in chicken - GW22246F from Sigma-Aldrich
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NHP2L1 antibody - N-terminal region (ARP40236_P050) - ARP40236_P050 from Aviva Systems Biology
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NHP2L1-Antibody-monoclonal-M02 - AT3049a from Abgent, a WuXi AppTec company
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NHP2L1 antibody - GTX15873 from GeneTex
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NHP2L1 antibody [N1C3] - GTX109247 from GeneTex
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NHP2L1 antibody - 70R-18877 from Fitzgerald
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NHP2 like protein 1 antibody - 70R-13262 from Fitzgerald
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