Grin2b

Gene Symbol	Grin2b
Entrez Gene	14812
Alt Symbol	AW490526, GluN2B, NR2B, Nmdar2b
Species	Mouse
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Other Description	GluRepsilon2|N-methyl D-aspartate receptor 2B|N-methyl D-aspartate receptor subtype 2B|glutamate [NMDA] receptor subunit epsilon-2|glutamate receptor ionotropic, NMDA 2B
Swissprots	Q01097 Q9DCB2
Accessions	EDL10558 Q01097 AJ459261 CAD30666 AJ459262 CAD30667 AJ459263 CAD30668 AK002963 BAB22483 AK013569 AK163195 BAE37231 BC172745 AAI72745 CF745896 D10651 BAA01498 XM_006505572 XP_006505635 XM_006505573 XP_006505636 XM_006505574 XP_006505637 XM_006505575 XP_006505638 XM_011241219 XP_011239521 XM_011241220 XP_011239522 XM_011241221 XP_011239523 NM_008171 NP_032197
Function	NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. {ECO:0000269|PubMed:20141836}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Top Pathways	Rap1 signaling pathway, Alcoholism, Cocaine addiction, Circadian entrainment, cAMP signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Glutamate [NMDA] receptor subunit epsilon-2 (GRIN2B), Mouse, ELISA Kit - CSB-EL009913MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

glutamate receptor, ionotropic, N-methyl D-aspartate 2B, ELISA Kit - MBS921793 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse GRIN2B is typically less than 7.8 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml -2000 pg/ml.

Mouse Glutamate [NMDA] receptor subunit epsilon-2(GRIN2B) ELISA kit - CSB-EL009913MO from Cusabio Category ELISA Kit Sensitivity 7.8pg/ml Range 31.25 pg/ml-2000 pg/ml

Mouse Glutamate [NMDA] receptor subunit epsilon-2 (GRIN2B) ELISA Kit - EKC36956 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7.8 pg/ml Range 31.25 pg/ml-2000 pg/ml

Mouse Grin2b ELISA Kit - E054386 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of mouse GRIN2B is typically less than 7.8 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mea

Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2B (GRIN2B), ELISA Kit - MBS450692 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.147ng/mL Range 0.312-20ng/mL

Glutamate [NMDA] Receptor Subunit Epsilon-2 (GRIN2B), ELISA Kit - MBS9350364 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse GRIN2B ELISA Kit - orb409070 from Biorbyt Category ELISA Kit Sensitivity 7.8pg/ml Range 31.25 pg/ml-2000 pg/ml

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