Grin2b

Gene Symbol Grin2b
Entrez Gene 14812
Alt Symbol AW490526, GluN2B, NR2B, Nmdar2b
Species Mouse
Gene Type protein-coding
Description glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Other Description GluRepsilon2|N-methyl D-aspartate receptor 2B|N-methyl D-aspartate receptor subtype 2B|glutamate [NMDA] receptor subunit epsilon-2|glutamate receptor ionotropic, NMDA 2B
Swissprots Q01097 Q9DCB2
Accessions EDL10558 Q01097 AJ459261 CAD30666 AJ459262 CAD30667 AJ459263 CAD30668 AK002963 BAB22483 AK013569 AK163195 BAE37231 BC172745 AAI72745 CF745896 D10651 BAA01498 XM_006505572 XP_006505635 XM_006505573 XP_006505636 XM_006505574 XP_006505637 XM_006505575 XP_006505638 XM_011241219 XP_011239521 XM_011241220 XP_011239522 XM_011241221 XP_011239523 NM_008171 NP_032197
Function NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. {ECO:0000269|PubMed:20141836}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Top Pathways Rap1 signaling pathway, Alcoholism, Cocaine addiction, Circadian entrainment, cAMP signaling pathway

NMDAε2 (A-8) - sc-365597 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NMDAε2 (A-8): sc-365597. Western blot analysis of NMDAε2 expression in rat hippocampus tissue extract.

NMDAR2B (Ab-1472) antibody (OAEC00503) - OAEC00503 from Aviva Systems Biology

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody - 70R-37594 from Fitzgerald

Prices $225.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody (Tyr1336) - 70R-34429 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

GRIN2B antibody - 70R-34638 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody (Tyr1474) - 70R-37245 from Fitzgerald

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody - 70R-34430 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody - 70R-36814 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody (Tyr1474) - 70R-35006 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B (N-term) antibody - AM32685PU-N from Acris Antibodies

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E4.25A4

Anti-NMDAR2B antibody - STJ70948 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

NMDAR2B, Polyclonal Antibody - MBS856858 from MyBioSource

Prices $180.00, $215.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B (Phospho-Tyr1474) Antibody - E11-0526A from Enogene

Prices $225.00
Sizes 100 μg
Host Rabbit

NMDAR2B (Ab-1472) antibody - E021158-1 from Enogene

Prices $100.00
Sizes 50μg/50μl
Host Rabbit

NMDAR2B (Ab-1472) antibody - E021158-2 from Enogene

Prices $170.00
Sizes 100μg/100μl
Host Rabbit

Anti-GRIN2B (aa 1200-1300) polyclonal antibody - DPABH-27835 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Rabbit Anti-Human GRIN2B Polyclonal Antibody - DPABH-27836 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Phospho-NMDAR2B pSer1480 Antibody - PA5-19491 from Thermo Fisher Scientific

Prices $339.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Phospho-NMDAR2B (Ser1166) Polyclonal Antibody - PA5-35401 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Phospho-NMDA Receptor 2B pSer1166 in rat hippocampal lysate using a Phospho-NMDA Receptor 2B pSer1166 polyclonal antibody (Product # PA5-35401). Results show a band at ~180kDa. Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (lane 2), but not by the corresponding dephospho-peptide (not shown).

Anti-NR2B Antibody - 06-600 from EMD Millipore

Prices $419.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal

NMDAR2B antibody - GTX130184 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-NMDAR2B antibody used in Western blot. GTX130184

anti-NMDAR2B antibody - ARG52363 from Arigo Biolaboratories

ARG52363 anti-NMDAR2B antibody WB image Western blot: 10 ug of rat hippocampal (Hipp) lysate stained with ARG52363 anti-NMDAR2B antibody showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.

anti-NMDAR2B antibody - ARG52362 from Arigo Biolaboratories

Host Rabbit
Clonality Polyclonal
ARG52362 anti-NMDAR2B antibody WB image Western Blot: 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor stained with ARG52362 NMDAR2B antibody
ARG51666 anti-NMDAR2B phospho (Tyr1474) antibody WB image Western Blot: extracts from A431 cells untreated or treated with EGF stained with anti-NMDAR2B (phospho Tyr1474) antibody ARG51666.

anti-NMDAR2B antibody - ARG51143 from Arigo Biolaboratories

ARG51143 anti-NMDAR2B antibody ICC/IF image Immunofluorescence: methanol-fixed HeLa cells stained with anti-NMDAR2B antibody ARG51143.
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