Grin2b

Gene Symbol Grin2b
Entrez Gene 14812
Alt Symbol AW490526, GluN2B, NR2B, Nmdar2b
Species Mouse
Gene Type protein-coding
Description glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Other Description GluRepsilon2|N-methyl D-aspartate receptor 2B|N-methyl D-aspartate receptor subtype 2B|glutamate [NMDA] receptor subunit epsilon-2|glutamate receptor ionotropic, NMDA 2B
Swissprots Q01097 Q9DCB2
Accessions EDL10558 Q01097 AJ459261 CAD30666 AJ459262 CAD30667 AJ459263 CAD30668 AK002963 BAB22483 AK013569 AK163195 BAE37231 BC172745 AAI72745 CF745896 D10651 BAA01498 XM_006505572 XP_006505635 XM_006505573 XP_006505636 XM_006505574 XP_006505637 XM_006505575 XP_006505638 XM_011241219 XP_011239521 XM_011241220 XP_011239522 XM_011241221 XP_011239523 NM_008171 NP_032197
Function NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. {ECO:0000269|PubMed:20141836}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Top Pathways Rap1 signaling pathway, Alcoholism, Cocaine addiction, Circadian entrainment, cAMP signaling pathway

NMDAε2 CRISPR/Cas9 KO Plasmid (m) - sc-420690 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 HDR Plasmid (m) - sc-420690-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 Double Nickase Plasmid (m) - sc-420690-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 Double Nickase Plasmid (m2) - sc-420690-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 CRISPR Activation Plasmid (m) - sc-420690-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 CRISPR Activation Plasmid (m2) - sc-420690-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 Lentiviral Activation Particles (m) - sc-420690-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 Lentiviral Activation Particles (m2) - sc-420690-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NMDAε2 siRNA (m) - sc-36086 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

NMDAε2 shRNA Plasmid (m) - sc-36086-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

NMDAε2 shRNA (m) Lentiviral Particles - sc-36086-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU067251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN32846 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32846 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GRIN2B siRNA (Mouse) - CRM1694 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GRIN2B - MBS8215037 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse GRIN2B (NM_008171.3) - SHH307914 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Grin2b(NM_008171.3) - SHH104771 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse GRIN2B siRNA - orb281170 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GRIN2B shRNA Plasmid (Mouse) - CHM1694 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

GRIN2B miRNA 3'UTR clone - MiUTR1M-05380 from Creative biogene

Species Reactivities Mouse
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