FLOT2

Gene Symbol FLOT2
Entrez Gene 2319
Alt Symbol ECS-1, ECS1, ESA, ESA1, M17S1
Species Human
Gene Type protein-coding
Description flotillin 2
Other Description Flotillin 2 (epidermal surface antigen 1)|epidermal surface antigen|flotillin-2|membrane component chromosome 17 surface marker 1|membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1)
Swissprots Q14254
Accessions EAW51152 EAW51154 EAW51155 EAW51158 EAW51161 EAW51162 Q14254 AK225491 BC003683 AAH03683 BC017292 AAH17292 BT019477 AAV38284 BT019478 AAV38285 CA390100 CR541784 CAG46583 CR542265 CAG47061 DQ892691 ABM83617 DQ895935 ABM86861 M60922 AAA65729 XM_005257950 XP_005258007 XM_005257952 XP_005258009 XM_005257953 XP_005258010 NM_004475 NP_004466
Function May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Subcellular Location Cell membrane {ECO:0000269|PubMed:20682791}; Peripheral membrane protein {ECO:0000269|PubMed:20682791}. Membrane, caveola {ECO:0000269|PubMed:20682791}; Peripheral membrane protein {ECO:0000269|PubMed:20682791}. Endosome {ECO:0000269|PubMed:20682791}. Note=Membrane-associated protein of caveolae.
Tissue Specificity In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Top Pathways Insulin signaling pathway

Flotillin-2 (C42A3) Rabbit mAb - 3436 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C42A3
Western blot analysis of extracts from various cell lines using Flotillin-2 (C42A3) Rabbit mAb.

Flotillin-2 (L294) Antibody - 3244 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using Flotillin-2 (L294) Antibody.

Flotillin-2 (A-16) - sc-30750 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Flotillin-2 (A-16): sc-30750. Western blot analysis of Flotillin-2 expression in HeLa (A) and A-375 (B) whole cell lysates.

Flotillin-2 (A-3) - sc-48398 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Flotillin-2 (A-3): sc-48398. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Flotillin-2 (B-6) - sc-28320 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Flotillin-2 (B-6): sc-28320. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing membrane and cytoplasmic staining of follicle and non-follicle cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Flotillin-2 (C-20) - sc-16645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Flotillin-2 (C-20): sc-16645. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells.

Flotillin-2 (H-90) - sc-25507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Flotillin-2 (H-90): sc-25507. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse brain tissue showing membrane localization.

Anti-Flotillin 2 antibody - ab96507 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Flotillin 2 antibody (ab96507) at 1/1000 dilution + HeLa S3 whole cell lysate at 30 µg

Anti-Flotillin 2 antibody - ab88498 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Flotillin 2 antibody (ab88498) at 1/500 dilution + Human Liver lysate at 50 µg

Anti-Flotillin 2 antibody - ab20399 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Flotillin 2 antibody (ab20399) at 1 µg/ml + Human lung lysate at 0.3 µg/ml

Anti-Flotillin 2 antibody - ab123376 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Flotillin 2 antibody (ab123376) at 1/500 dilutionLane 1 : JK cell extract Lane 2 : HUVEC cell extract Lane 3 : HepG2 cell extract Lane 4 : HeLa cell extract

Anti-Flotillin 2 antibody - ab135389 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Flotillin 2 antibody (ab135389) at 1/500 dilution + A549 cell extract at 30 µg

Anti-Flotillin 2 antibody [EPR14128(B)] - ab181988 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14128(B)
All lanes : Anti-Flotillin 2 antibody [EPR14128(B)] (ab181988) at 1/4000 dilutionLane 1 : 293 cell lysateLane 2 : Hela cell lysateLane 3 : A375 cell lysateLane 4 : A549 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-FLOT2 / Flotillin 2 Antibody (aa365-428) - LS-C185355 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Lung CA using Flotillin-2 antibody at 1:100 dilution.

Anti-FLOT2 / Flotillin 2 Antibody (aa415-428) IHC-plus™ - LS-B4923 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-FLOT2 / Flotillin 1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4923 concentration 3.75 ug/ml.

Anti-FLOT2 / Flotillin 2 Antibody - LS-C307572 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-FLOT2 / Flotillin 2 Antibody - LS-C307573 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FLOT2 / Flotillin 2 Antibody (Arg144) - LS-C177248 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Flotillin-2 (R144) pAb in extracts from A549 cells.

Anti-FLOT2 / Flotillin 2 Antibody - LS-C335691 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using FLOT2 antibody.

Anti-FLOT2 / Flotillin 2 Antibody (aa420-424) - LS-C205173 from LifeSpan Bioscience

Prices $265.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of extract from JK, HUVEC, HepG2 and HeLa cells using ESA (FLOT2) antibody

Anti-FLOT2 / Flotillin 2 Antibody (aa95-144) IHC-plus™ - LS-B11418 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FLOT2 / Flotillin 2 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11418 concentration 20 ug/ml.

Anti-FLOT2 / Flotillin 2 Antibody (aa117-131) - LS-C313158 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of FLOT2 / Flotillin 2 antibody. Lane 1: Rat Lung Tissue Lysate. Lane 2: 293T Cell Lysate..

Flotillin 2 Antibody - NBP1-30881 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Flotillin 2 Antibody [NBP1-30881] - Analysis of paraformaldehyde-fixed HeLaS3, using antibody at 1:100 dilution.

Flotillin 2 Antibody - NBP1-84910 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Flotillin 2 Antibody [NBP1-84910] - Analysis in human cell line RT-4.

Flotillin 2 Antibody - NBP2-16507 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Flotillin 2 Antibody [NBP2-16507] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.
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