| Gene Symbol |
B3GALT6
|
| Entrez Gene |
126792
|
| Alt Symbol |
EDSP2, SEMDJL1, beta3GalT6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
|
| Other Description |
GAG GalTII|UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 6|beta-1,3-GalTase 6|beta-1,3-galactosyltransferase 6|beta3Gal-T6|galactosyltransferase II|galactosylxylosylprotein 3-beta-galactosyltransferase
|
| Swissprots |
Q5T7M5 Q96L58
|
| Accessions |
EAW56269 Q96L58 BC015549 BC041621 BC051719 AAH51719 BC160034 AAI60034 BE249959 BF002665 BG290330 NM_080605 NP_542172
|
| Function |
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues. {ECO:0000269|PubMed:11551958}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:11551958}; Single-pass type II membrane protein {ECO:0000269|PubMed:11551958}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:11551958}.
|
| Top Pathways |
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin
|