Gene Symbol | B3GALT6 |
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Entrez Gene | 126792 |
Alt Symbol | EDSP2, SEMDJL1, beta3GalT6 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 |
Other Description | GAG GalTII|UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 6|beta-1,3-GalTase 6|beta-1,3-galactosyltransferase 6|beta3Gal-T6|galactosyltransferase II|galactosylxylosylprotein 3-beta-galactosyltransferase |
Swissprots | Q5T7M5 Q96L58 |
Accessions | EAW56269 Q96L58 BC015549 BC041621 BC051719 AAH51719 BC160034 AAI60034 BE249959 BF002665 BG290330 NM_080605 NP_542172 |
Function | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues. {ECO:0000269|PubMed:11551958}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:11551958}; Single-pass type II membrane protein {ECO:0000269|PubMed:11551958}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11551958}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Human B3GALT6 protein fragment - ab165262 from Abcam
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B3GALT6 Antibody Blocking Peptide - LS-E7691 from LifeSpan Bioscience
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B3GALT6 Antibody Blocking Peptide - LS-E18156 from LifeSpan Bioscience
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Recombinant Human B3GALT6 Protein - H00126792-Q01 from Novus Biologicals
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B3GALT6-Antibody-C-term-Blocking-Peptide - BP5011b from Abgent, a WuXi AppTec company
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B3GALT6 Blocking Peptide - 33R-9759 from Fitzgerald
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B3GALT6 Blocking Peptide - 33R-2691 from Fitzgerald
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B3GALT6 Blocking Peptide - abx161024 from Abbexa
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B3GALT6 - H00126792-Q01-10 from Acris Antibodies
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B3GALT6 - H00126792-Q01-25 from Acris Antibodies
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B3GALT6 Blocking Peptide - CBP3523 from Cohesion Biosciences
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Recombinant Human Beta-1,3-galactosyltransferase 6(B3GALT6) - CSB-YP853453HU CSB-EP853453HU CSB-BP853453HU CSB-MP853453HU from Cusabio
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B3GALT6 Peptide, Human - M34GP01261H from Creative Peptides
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B3GALT6 peptide - orb234398 from Biorbyt
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Recombinant Human B3GALT6 protein, GST-tagged - B3GALT6-012H from Creative Biomart
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