TNFSF13

Gene Symbol TNFSF13
Entrez Gene 8741
Alt Symbol APRIL, CD256, TALL-2, TALL2, TRDL-1, UNQ383/PRO715, ZTNF2
Species Human
Gene Type protein-coding
Description tumor necrosis factor (ligand) superfamily, member 13
Other Description TNF- and APOL-related leukocyte expressed ligand 2|a proliferation-inducing ligand|tumor necrosis factor ligand superfamily member 13|tumor necrosis factor-like protein ZTNF2|tumor necrosis factor-related death ligand-1
Swissprots B4DVT2 Q541E1 Q9P1M9 A8MYD5 Q96HV6 Q9P1M8 Q5U0G8 O75888
Accessions AAM47279 ABK41890 BAE16556 CAZ39531 CBH32718 CBI67654 CBX33275 EAW90175 O75888 AF046888 AAC61312 AF114011 AAF59828 AF114012 AAF59829 AF114013 AAF59830 AF136294 AAD29422 AF184972 AAF01321 AI828515 AK090698 BAG52214 AK225556 AK301221 BAG62794 AK314518 AY081050 AAL90442 AY358880 AAQ89239 AY377858 AAQ91388 BC008042 AAH08042 BF793371 BI764562 BI910977 BT019561 AAV38368 BT019562 AAV38369 CR542040 CAG46837 CR542073 CAG46870 DQ149579 ABA39072 EF211088 ABQ88322 EU831984 ACE87425 EU832077 ACE86739 NM_001198622 NP_001185551 NM_001198623 NP_001185552 NM_001198624 NP_001185553 NM_003808 NP_003799 NM_172087 NP_742084 NM_172088 NP_742085 NR_073490
Function Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. {ECO:0000269|PubMed:10973284}.
Subcellular Location Secreted {ECO:0000269|PubMed:11571266}.
Tissue Specificity Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Top Pathways Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Rheumatoid arthritis

APRIL (F-5) - sc-374673 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
APRIL (F-5): sc-374673. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.

APRIL (H-10) - sc-374674 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
APRIL (H-10): sc-374674. Western blot analysis of APRIL expression in non-transfected (A) and human APRIL transfected (B) TNFSF12 whole cell lysates.

APRIL (H-60) - sc-28919 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

APRIL (N-16) - sc-5737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APRIL (R-15) - sc-5739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
APRIL (R-15): sc-5739. Western blot analysis of APRIL expression in M1 whole cell lysate.

APRIL (Sacha-1) - sc-57035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rat
Clonality Monoclonal
APRIL (Sacha-1): sc-57035. Intracellular FCM analysis of fixed and permeabilized non-transfected (thin line) and APRIL transfected (thick line) 293T cells.

Anti-APRIL antibody - ab64967 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-APRIL antibody (ab64967) at 1/500 dilutionLane 1 : extracts from HeLa cells without immunising peptideLane 2 : extracts from COLO205 cells, without immunising peptideLane 3 : extracts from COLO205 cells, with immunising peptide

Anti-APRIL antibody - ab189263 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells labeling APRIL using ab189263 at 1/100 dilution. The picture on the right is treated with the synthesized peptide.

Anti-APRIL antibody - ab3681 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-APRIL antibody (ab3681) at 1 µg/mlLane 2 : Anti-APRIL antibody (ab3681) at 2 µg/mlLane 3 : Anti-APRIL antibody (ab3681) at 4 µg/mlLane 1 : Jurkat cellsLane 2 : Jurkat cellsLane 3 : Jurkat cells

Anti-APRIL antibody - ab3680 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-APRIL antibody (ab3680) at 5 µg/mlLane 2 : Anti-APRIL antibody (ab3680) at 10 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysate

Anti-APRIL antibody - ab109566 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-APRIL antibody [Aprily-1] - ab16088 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone Aprily-1
ab16088 at 10ug/ml detecting APRIL by FACS analysis.Left hand panel mock transfected cellsRight hand panel human APRIL tranfected cellsHEK 293 cells were mock transfected or transfected with an expression plasmid enabling surface expression of a non-cleavable human APRIL. Cells (5x105) were incubated on ice for 30 min in 50 ul FACS buffer (PBS, 5% Fetal calf serum, 0.02% azide) containing 10ug/ml of Aprily-1 antibody. After washing in FACS buffer, FITC-conjugated antibody to mouse IgG was added. Cells were incubated on ice for 30 min., washed and analyzed by flow cytometry.

Anti-APRIL antibody (Biotin) - ab84029 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-APRIL antibody [EPR4286] - ab108206 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4286
All lanes : Anti-APRIL antibody [EPR4286] (ab108206) at 1/1000 dilutionLane 1 : Raji cell lysateLane 2 : Jurkat cell lysateLane 3 : HeLa cell lysateLane 4 : PC-12 cell lysateLane 5 : NIH 3T3 cell lysateLysates/proteins at 10 µg per lane.

Anti-APRIL antibody [Sacha-1] - ab16085 from Abcam

Prices $376.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone Sacha-1
ab16085 at 1ug/ml detecting  membrane-bound human APRIL on HEK 293T cells by FACS analysis. HEK 293T cells (5x105) were mock transfected (thin line) or transfected with an expression plasmid enabling surface expression of a non-cleavable mouse APRIL (thick line). Cells were incubated on ice for 30 min. in 50ul FACS buffer (PBS, 5% fetal calf serum, 0.02% azide) containing 1ug/ml of MAb to APRIL (Sacha-1). After washing in FACS buffer, PE-conjugated antibody to rat IgG was added. Cells were incubated on ice for 30 min., washed and then analyzed by flow cytometry.

Anti-TNFSF13 / APRIL Antibody - LS-C18653 from LifeSpan Bioscience

Prices $370.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-TNFSF13 / APRIL Antibody (clone Aprily-1) - LS-C18658 from LifeSpan Bioscience

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Aprily-1

Anti-TNFSF13 / APRIL Antibody - LS-C18659 from LifeSpan Bioscience

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TNFSF13 / APRIL Antibody (aa105-250) - LS-C18689 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-TNFSF13 / APRIL Antibody (aa93-233) - LS-C18687 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TNFSF13 / APRIL Antibody (Biotin) - LS-C104484 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 25 µg, 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TNFSF13 / APRIL Antibody (Biotin) - LS-C104462 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 25 µg, 50 µg
Host Goat
Clonality Polyclonal

Anti-TNFSF13 / APRIL Antibody - LS-C126874 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TNFSF13 / APRIL Antibody - LS-C126876 from LifeSpan Bioscience

Prices $405.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF13 / APRIL Antibody - LS-C153088 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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