TNFSF13
| Gene Symbol | TNFSF13 |
|---|---|
| Entrez Gene | 8741 |
| Alt Symbol | APRIL, CD256, TALL-2, TALL2, TRDL-1, UNQ383/PRO715, ZTNF2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | tumor necrosis factor (ligand) superfamily, member 13 |
| Other Description | TNF- and APOL-related leukocyte expressed ligand 2|a proliferation-inducing ligand|tumor necrosis factor ligand superfamily member 13|tumor necrosis factor-like protein ZTNF2|tumor necrosis factor-related death ligand-1 |
| Swissprots | B4DVT2 Q541E1 Q9P1M9 A8MYD5 Q96HV6 Q9P1M8 Q5U0G8 O75888 |
| Accessions | AAM47279 ABK41890 BAE16556 CAZ39531 CBH32718 CBI67654 CBX33275 EAW90175 O75888 AF046888 AAC61312 AF114011 AAF59828 AF114012 AAF59829 AF114013 AAF59830 AF136294 AAD29422 AF184972 AAF01321 AI828515 AK090698 BAG52214 AK225556 AK301221 BAG62794 AK314518 AY081050 AAL90442 AY358880 AAQ89239 AY377858 AAQ91388 BC008042 AAH08042 BF793371 BI764562 BI910977 BT019561 AAV38368 BT019562 AAV38369 CR542040 CAG46837 CR542073 CAG46870 DQ149579 ABA39072 EF211088 ABQ88322 EU831984 ACE87425 EU832077 ACE86739 NM_001198622 NP_001185551 NM_001198623 NP_001185552 NM_001198624 NP_001185553 NM_003808 NP_003799 NM_172087 NP_742084 NM_172088 NP_742085 NR_073490 |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. {ECO:0000269|PubMed:10973284}. |
| Subcellular Location | Secreted {ECO:0000269|PubMed:11571266}. |
| Tissue Specificity | Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
| Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Rheumatoid arthritis |
Human APRIL full length protein - ab160170 from Abcam
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Human APRIL full length protein - ab177605 from Abcam
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Human APRIL protein fragment - ab177588 from Abcam
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Mouse APRIL full length protein - ab128556 from Abcam
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Mouse APRIL protein fragment - ab50096 from Abcam
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Pig APRIL full length protein - ab151199 from Abcam
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Rat APRIL protein fragment - ab136371 from Abcam
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TNFSF13 / APRIL Antibody Blocking Peptide - LS-E22301 from LifeSpan Bioscience
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TNFSF13 / APRIL Antibody Blocking Peptide - LS-E29918 from LifeSpan Bioscience
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TNFSF13 / APRIL Antibody Blocking Peptide - LS-E29961 from LifeSpan Bioscience
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TNFSF13 / APRIL Antibody Blocking Peptide - LS-E27070 from LifeSpan Bioscience
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APRIL/TNFSF13 Recombinant Protein - H00008741-P01 from Novus Biologicals
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APRIL/TNFSF13 Blocking Peptide - NBP1-76767PEP from Novus Biologicals
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APRIL/TNFSF13 Peptide - NBP1-76461PEP from Novus Biologicals
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APRIL Recombinant Protein (Active) - GTX48108-PRO from GeneTex
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Recombinant Human APRIL/TNFSF13 (HEK293-expressed) - 5860-AP-010 from R&D Systems
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Recombinant Human APRIL/TNFSF13 (HEK293-expressed), CF - 5860-AP-010/CF from R&D Systems
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APRIL protein - 30R-AA022 from Fitzgerald
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APRIL protein - 30R-AA042 from Fitzgerald
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TNFSF13 Blocking Peptide - 33R-2678 from Fitzgerald
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CD256 Blocking Peptide - abx063512 from Abbexa
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Human TNFSF13 Protein - abx069548 from Abbexa
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CD256 / APRIL - AR20000PU-N from Acris Antibodies
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CD256 / APRIL - AR20000PU-S from Acris Antibodies
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CD256 / APRIL (105-247, T7 tag) - AR51422PU-N from Acris Antibodies
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