TNFSF13
| Gene Symbol | TNFSF13 |
|---|---|
| Entrez Gene | 8741 |
| Alt Symbol | APRIL, CD256, TALL-2, TALL2, TRDL-1, UNQ383/PRO715, ZTNF2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | tumor necrosis factor (ligand) superfamily, member 13 |
| Other Description | TNF- and APOL-related leukocyte expressed ligand 2|a proliferation-inducing ligand|tumor necrosis factor ligand superfamily member 13|tumor necrosis factor-like protein ZTNF2|tumor necrosis factor-related death ligand-1 |
| Swissprots | B4DVT2 Q541E1 Q9P1M9 A8MYD5 Q96HV6 Q9P1M8 Q5U0G8 O75888 |
| Accessions | AAM47279 ABK41890 BAE16556 CAZ39531 CBH32718 CBI67654 CBX33275 EAW90175 O75888 AF046888 AAC61312 AF114011 AAF59828 AF114012 AAF59829 AF114013 AAF59830 AF136294 AAD29422 AF184972 AAF01321 AI828515 AK090698 BAG52214 AK225556 AK301221 BAG62794 AK314518 AY081050 AAL90442 AY358880 AAQ89239 AY377858 AAQ91388 BC008042 AAH08042 BF793371 BI764562 BI910977 BT019561 AAV38368 BT019562 AAV38369 CR542040 CAG46837 CR542073 CAG46870 DQ149579 ABA39072 EF211088 ABQ88322 EU831984 ACE87425 EU832077 ACE86739 NM_001198622 NP_001185551 NM_001198623 NP_001185552 NM_001198624 NP_001185553 NM_003808 NP_003799 NM_172087 NP_742084 NM_172088 NP_742085 NR_073490 |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. {ECO:0000269|PubMed:10973284}. |
| Subcellular Location | Secreted {ECO:0000269|PubMed:11571266}. |
| Tissue Specificity | Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
| Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Rheumatoid arthritis |
APRIL CRISPR/Cas9 KO Plasmid (h) - sc-403150 from Santa Cruz Biotechnology
|
||||||||
APRIL HDR Plasmid (h) - sc-403150-HDR from Santa Cruz Biotechnology
|
||||||||
APRIL Double Nickase Plasmid (h) - sc-403150-NIC from Santa Cruz Biotechnology
|
||||||||
APRIL Double Nickase Plasmid (h2) - sc-403150-NIC-2 from Santa Cruz Biotechnology
|
||||||||
APRIL CRISPR Activation Plasmid (h) - sc-403150-ACT from Santa Cruz Biotechnology
|
||||||||
APRIL CRISPR Activation Plasmid (h2) - sc-403150-ACT-2 from Santa Cruz Biotechnology
|
||||||||
APRIL Lentiviral Activation Particles (h) - sc-403150-LAC from Santa Cruz Biotechnology
|
||||||||
APRIL Lentiviral Activation Particles (h2) - sc-403150-LAC-2 from Santa Cruz Biotechnology
|
||||||||
APRIL siRNA (h) - sc-39822 from Santa Cruz Biotechnology
|
||||||||
APRIL shRNA Plasmid (h) - sc-39822-SH from Santa Cruz Biotechnology
|
||||||||
APRIL shRNA (h) Lentiviral Particles - sc-39822-V from Santa Cruz Biotechnology
|
||||||||
APRIL/TNFSF13 RNAi - H00008741-R03 from Novus Biologicals
|
||||||||
APRIL/TNFSF13 RNAi - H00008741-R02 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21763 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21763 from Sigma-Aldrich
|
||||||||
TNFSF13 siRNA (Human) - CRH5759 from Cohesion Biosciences
|
||||||||
APRIL/TNFSF13 RNAi - H00008741-R01 from Novus Biologicals
|
||||||||
TNFSF13 - MBS8238299 from MyBioSource
|
||||||||
shRNA set against Human TNFSF13 (NM_003808.3) - SHH432124 from Creative biogene
|
||||||||
TNFSF13 shRNA Plasmid (Human) - CHH5759 from Cohesion Biosciences
|
||||||||
TNFSF13 miRNA 3'UTR clone - MiUTR3H-06829 from Creative biogene
|
||||||||
TNFSF13 miRNA 3'UTR clone - MiUTR3H-06830 from Creative biogene
|
||||||||
TNFSF13 miRNA 3'UTR clone - MiUTR3H-06831 from Creative biogene
|