ARL2

Gene Symbol ARL2
Entrez Gene 402
Alt Symbol ARFL2
Species Human
Gene Type protein-coding
Description ADP-ribosylation factor-like 2
Other Description ADP-ribosylation factor-like protein 2
Swissprots G3V184 P36404 Q9BUK8
Accessions EAW74332 EAW74333 P36404 AF493888 AAM12602 AI076058 AI631767 AK223502 BAD97222 AK294580 BAG57771 BC002530 AAH02530 BG706294 BT006674 AAP35320 CN338497 EU832671 ACE87762 EU832750 ACE87082 L13687 AAC37606 NM_001199745 NP_001186674 NM_001667 NP_001658
Function Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle. {ECO:0000269|PubMed:10831612, ECO:0000269|PubMed:16525022, ECO:0000269|PubMed:18234692, ECO:00002
Subcellular Location Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. {ECO:0000250}.

ARL2 (C-15) - sc-26119 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARL2 (N-20) - sc-130118 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ARL2 (N-20): sc-130118. Western blot analysis of ARL2 expression in Hela whole cell lysate.

Anti-ARL2 antibody - ab3391 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab3391 staining (2µg/ml) of U937 lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence.

Anti-ARL2 antibody - ab109742 from Abcam

Prices $407.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ARL2 antibody (ab109742) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-ARL2 antibody - ab151502 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ARL2 antibody (ab151502) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-ARL2 antibody - ab129799 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ARL2 antibody (ab129799) at 1/100 dilution + T47D cell lysate at 35 µg

Anti-ARL2 antibody [EPR14436] - ab183510 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14436
All lanes : Anti-ARL2 antibody [EPR14436] (ab183510) at 1/10000 dilutionLane 1 : T47D cell lysateLane 2 : A549 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-ARL2 antibody - N-terminal - ab71288 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ARL2 antibody - N-terminal (ab71288) at 1/100 dilution + Hela cell line lysate at 35 µg/ml

Anti-ARL2 Antibody IHC-plus™ - LS-B4071 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ARL2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4071 concentration 10 ug/ml.

Anti-ARL2 Antibody (aa146-157) - LS-C54535 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (2 ug/ml) of U937 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-ARL2 Antibody (Biotin) - LS-C183100 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (FITC) - LS-C183101 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (HRP) - LS-C183102 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (Biotin) - LS-C211101 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody - LS-C189957 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody - LS-C211104 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (FITC) - LS-C211102 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (HRP) - LS-C211103 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (N-Terminus) - LS-C99657 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-ARL2 antibody in HeLa cell line lysate (35 ug/lane). ARL2(arrow) was detected using the purified antibody.

Anti-ARL2 Antibody (C-Terminus, PE) - LS-C251716 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (aa54-82, APC) - LS-C251718 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (aa54-82, PE) - LS-C251720 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (N-Terminus, APC) - LS-C275238 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (C-Terminus, AP) - LS-C251714 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARL2 Antibody (C-Terminus, APC) - LS-C251715 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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