ARL2

Gene Symbol	ARL2
Entrez Gene	402
Alt Symbol	ARFL2
Species	Human
Gene Type	protein-coding
Description	ADP-ribosylation factor-like 2
Other Description	ADP-ribosylation factor-like protein 2
Swissprots	G3V184 P36404 Q9BUK8
Accessions	EAW74332 EAW74333 P36404 AF493888 AAM12602 AI076058 AI631767 AK223502 BAD97222 AK294580 BAG57771 BC002530 AAH02530 BG706294 BT006674 AAP35320 CN338497 EU832671 ACE87762 EU832750 ACE87082 L13687 AAC37606 NM_001199745 NP_001186674 NM_001667 NP_001658
Function	Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle. {ECO:0000269|PubMed:10831612, ECO:0000269|PubMed:16525022, ECO:0000269|PubMed:18234692, ECO:00002
Subcellular Location	Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ARL2 full length protein - ab103471 from Abcam Category Protein Prices $235.00, $866.00 Sizes 100 µg, 500 µg Source E. coli Species Human

ARL2 Antibody Blocking Peptide - LS-E4349 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL2 Antibody Blocking Peptide - LS-E25399 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL2 Antibody Blocking Peptide - LS-E6936 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL2 Recombinant Protein - H00000402-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human ARL2 Protein - NBP1-50929 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

ARL2 Peptide - P1036 from Novus Biologicals Category Peptide Species Human

ARL2-Antibody-Center-Blocking-Peptide - BP16648c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARL2-Antibody-N-term-Blocking-Peptide - BP2305a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARL2 blocking peptide - GTX89899-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

ARL2 Protein (OPPA00050) - OPPA00050 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human ARL2 protein - orb167918 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human ARL2 protein - orb245071 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

ARL2 protein (His tag) - 80R-1604 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

ARL2 Peptide - AC21-0227-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ARL2 (1-184, His-tag) - AR09785PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ARL2 (1-184, His-tag) - AR09785PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ARL2 - H00000402-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

ADP-Ribosylation Factor-Like 2, Human Recombinant - 228-12794-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human ADP-Ribosylation Factor-Like 2 - 228-12794-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human ADP-Ribosylation Factor-Like 2 - 228-12794-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

ARL2, 1-184aa, Human, His tag, E.coli - 01-1904-2 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ARL2 Peptide - 45-285P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ARL2 fusion protein - Ag0334 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ARL2 fusion protein - Ag14443 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

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