WHSC1L1

Gene Symbol	WHSC1L1
Entrez Gene	54904
Alt Symbol	NSD3, pp14328
Species	Human
Gene Type	protein-coding
Description	Wolf-Hirschhorn syndrome candidate 1-like 1
Other Description	WHSC1-like 1 isoform 9 with methyltransferase activity to lysine|WHSC1-like protein 1|histone-lysine N-methyltransferase NSD3|nuclear SET domain-containing protein 3|protein whistle
Swissprots	Q9BYU8 D3DSX1 Q9BZ95 Q9NXA6 Q1RMD3 Q9H9W9 B7ZL11 Q6ZSA5 Q9BYU9 Q3B796 Q9H2M8
Accessions	EAW63319 EAW63320 EAW63321 EAW63322 Q9BZ95 AF255649 AAG44637 AF318339 AAL55846 AF332468 AAK00354 AF332469 AAK00355 AJ295990 CAC28350 AJ295991 CAC28351 AJ295992 CAC28352 AK000360 BAA91110 AK022560 BAB14099 AK023534 AK025702 AK092166 AK127594 AL832895 BC000030 BC007787 BC012059 AAH12059 BC062631 AAH62631 BC073858 BC101717 AAI01718 BC107734 AAI07735 BC113469 AAI13470 BC115006 AAI15007 BC115007 BC143510 AAI43511 JF432144 ADZ15361 XM_005273547 XP_005273604 XM_005273548 XP_005273605 XM_011544561 XP_011542863 XM_011544562 XP_011542864 XM_011544563 XP_011542865 NM_017778 NP_060248 NM_023034 NP_075447
Function	Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. {ECO:0000269|PubMed:16682010}.
Subcellular Location	Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
Tissue Specificity	Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. {ECO:0000269|PubMed:11374904}.
Top Pathways	Lysine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NSD3 peptide - ab14995 from Abcam Category Peptide

Human NSD3 protein fragment - ab196390 from Abcam Category Protein Source E. coli Species Human

NSD3 / WHSC1L1 Antibody Blocking Peptide - LS-E1919 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NSD3 Protein - H00054904-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

WHSC1L1-Antibody-N-term-Blocking-peptide - BP12757a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WHSC1L1 / NSD3 - H00054904-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

WHSC1L1 fusion protein - ag1894 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant WHSC1L1 / NSD3 - SET protein - 31477 from ActiveMotif Category Protein Prices $395.00, $3,500.00 Sizes 50 µg, 1 mg Source E. coli Species Human

Recombinant Human WHSC1L1, His-tagged - WHSC1L1-28412TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human WHSC1L1, GST-tagged - WHSC1L1-3729H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Histone-lysine N-methyltransferase NSD3(WHSC1L1) ,partial - CSB-YP880145HU CSB-EP880145HU CSB-BP880145HU CSB-MP880145HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human WHSC1L1 protein, GST-tagged - WHSC1L1-186H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human WHSC1L1 Protein, GST-tagged - WHSC1L1-148H from Creative Biomart Category Protein Source E. coli Species Human

NSD3 Recombinant Protein Antigen - NBP1-89852PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NSD3 Recombinant Protein Antigen - NBP1-89851PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WHSC1L1 Antibody - SH-A16845 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

WHSC1L1-Antibody-C-term-Blocking-Peptide - BP1904a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WHSC1L1 Peptide, Human - M34GP17493H from Creative Peptides Category Peptide Source Synthetic. Species Human

Histone-lysine N-methyltransferase NSD3 (WHSC1L1), partial, Recombinant Protein - MBS1454544 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human WHSC1L1 Protein (1-645 aa), His-tagged - WHSC1L1-2631H from Creative Biomart Category Protein Source Yeast Species Human

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