| Gene Symbol |
LILRA4
|
| Entrez Gene |
23547
|
| Alt Symbol |
CD85g, ILT7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
|
| Other Description |
CD85 antigen-like family member G|immunoglobulin-like transcript 7|leukocyte immunoglobulin-like receptor subfamily A member 4|leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4
|
| Swissprots |
P59901 Q32MC4
|
| Accessions |
EAW72230 EAW72231 EAW72232 P59901 AF041261 AAD02203 AF283989 AAL36993 BC038829 BC109198 AAI09199 BC109199 AAI09200 BI834628 BI834924 DA983933 NM_012276 NP_036408
|
| Function |
May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4. {ECO:0000269|PubMed:12529506}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Detected in eosinophils, neutrophils and monocytes. {ECO:0000269|PubMed:12529506}.
|
| Top Pathways |
Osteoclast differentiation
|