Gene Symbol | LILRA4 |
---|---|
Entrez Gene | 23547 |
Alt Symbol | CD85g, ILT7 |
Species | Human |
Gene Type | protein-coding |
Description | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
Other Description | CD85 antigen-like family member G|immunoglobulin-like transcript 7|leukocyte immunoglobulin-like receptor subfamily A member 4|leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4 |
Swissprots | P59901 Q32MC4 |
Accessions | EAW72230 EAW72231 EAW72232 P59901 AF041261 AAD02203 AF283989 AAL36993 BC038829 BC109198 AAI09199 BC109199 AAI09200 BI834628 BI834924 DA983933 NM_012276 NP_036408 |
Function | May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4. {ECO:0000269|PubMed:12529506}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Detected in eosinophils, neutrophils and monocytes. {ECO:0000269|PubMed:12529506}. |
Top Pathways | Osteoclast differentiation |