Gene Symbol | LILRA4 |
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Entrez Gene | 23547 |
Alt Symbol | CD85g, ILT7 |
Species | Human |
Gene Type | protein-coding |
Description | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
Other Description | CD85 antigen-like family member G|immunoglobulin-like transcript 7|leukocyte immunoglobulin-like receptor subfamily A member 4|leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4 |
Swissprots | P59901 Q32MC4 |
Accessions | EAW72230 EAW72231 EAW72232 P59901 AF041261 AAD02203 AF283989 AAL36993 BC038829 BC109198 AAI09199 BC109199 AAI09200 BI834628 BI834924 DA983933 NM_012276 NP_036408 |
Function | May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4. {ECO:0000269|PubMed:12529506}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Detected in eosinophils, neutrophils and monocytes. {ECO:0000269|PubMed:12529506}. |
Top Pathways | Osteoclast differentiation |
ILT-7 CRISPR/Cas9 KO Plasmid (h) - sc-411763 from Santa Cruz Biotechnology
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ILT-7 HDR Plasmid (h) - sc-411763-HDR from Santa Cruz Biotechnology
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ILT-7 Double Nickase Plasmid (h) - sc-411763-NIC from Santa Cruz Biotechnology
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ILT-7 Double Nickase Plasmid (h2) - sc-411763-NIC-2 from Santa Cruz Biotechnology
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ILT-7 CRISPR Activation Plasmid (h) - sc-411763-ACT from Santa Cruz Biotechnology
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ILT-7 CRISPR Activation Plasmid (h2) - sc-411763-ACT-2 from Santa Cruz Biotechnology
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ILT-7 Lentiviral Activation Particles (h) - sc-411763-LAC from Santa Cruz Biotechnology
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ILT-7 Lentiviral Activation Particles (h2) - sc-411763-LAC-2 from Santa Cruz Biotechnology
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ILT-7 siRNA (h) - sc-97217 from Santa Cruz Biotechnology
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ILT-7 shRNA Plasmid (h) - sc-97217-SH from Santa Cruz Biotechnology
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ILT-7 shRNA (h) Lentiviral Particles - sc-97217-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU111531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11709 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11709 from Sigma-Aldrich
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LILRA4 siRNA (Human) - CRH8349 from Cohesion Biosciences
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ILT7/CD85g/LILRA4 RNAi - H00023547-R02 from Novus Biologicals
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shRNA set against Human LILRA4 (NM_012276.3) - SHH330275 from Creative biogene
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Human LILRA4 siRNA - orb268851 from Biorbyt
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LILRA4 shRNA Plasmid (Human) - CHH8349 from Cohesion Biosciences
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LILRA4 miRNA 3'UTR clone - MiUTR1H-05670 from Creative biogene
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