TBX6

Gene Symbol TBX6
Entrez Gene 6911
Alt Symbol SCDO5
Species Human
Gene Type protein-coding
Description T-box 6
Other Description T-box protein 6|T-box transcription factor TBX6
Swissprots O95947 Q9HA44 Q8TAS4
Accessions CAB37938 EAW79926 EAW79927 O95947 AJ007989 CAA07812 AK022330 BAB14014 BC026031 AAH26031 EU446659 ABZ92188 KJ534981 AHW56621 KJ535035 AHW56674 XM_005255523 XP_005255580 XM_011545926 XP_011544228 XR_950840 NM_004608 NP_004599 NM_080758
Function T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}.
Tissue Specificity Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.

TBX6 CRISPR/Cas9 KO Plasmid (h) - sc-405632 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 HDR Plasmid (h) - sc-405632-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 Double Nickase Plasmid (h) - sc-405632-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 Double Nickase Plasmid (h2) - sc-405632-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 CRISPR Activation Plasmid (h) - sc-405632-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 CRISPR Activation Plasmid (h2) - sc-405632-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 Lentiviral Activation Particles (h) - sc-405632-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 Lentiviral Activation Particles (h2) - sc-405632-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 siRNA (h) - sc-106773 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBX6 shRNA Plasmid (h) - sc-106773-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBX6 shRNA (h) Lentiviral Particles - sc-106773-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU052981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21115 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21115 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05564 from Sigma-Aldrich

Category miRNA

TBX6 siRNA (Human) - CRH4737 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TBX6 RNAi - H00006911-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TBX6 RNAi - H00006911-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TBX6 - MBS8230890 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TBX6 CRISPR/Cas9 KO Plasmid (h2) - sc-405632-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBX6 HDR Plasmid (h2) - sc-405632-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human TBX6 (NM_004608.3) - SHH424476 from Creative biogene

Category siRNA
Species Reactivities Human

TBX6 shRNA Plasmid (Human) - CHH4737 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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