DSP

Gene Symbol	DSP
Entrez Gene	1832
Alt Symbol	DCWHKTA, DP, DPI, DPII
Species	Human
Gene Type	protein-coding
Description	desmoplakin
Other Description	250/210 kDa paraneoplastic pemphigus antigen|desmoplakin I|desmoplakin II
Swissprots	D7RX09 P15924 Q9UHN4 O75993 Q14189 B2RTT2
Accessions	CAP07480 CAP07499 CAP11448 CAP11467 CAR97062 CAR97081 CAT82278 CAT82313 EAW55215 P15924 AB209992 BAE06074 AB621818 BAK64154 AF139065 AAF19785 AI304615 AK130229 BAC85309 AK296756 BAG59338 AK301676 BAG63149 AK304182 BAG65062 AL713599 AL713610 AW890985 BC140802 AAI40803 BC144587 CN282963 HM151899 ADI58529 J05211 AAA35766 M77830 AAA85135 XM_011514323 XP_011512625 NM_001008844 NP_001008844 NM_004415 NP_004406
Function	Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin- plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Subcellular Location	Cell junction, desmosome {ECO:0000269|PubMed:12802069}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12802069}. Note=Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network.
Tissue Specificity	Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.
Top Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Desmoplakin I+II peptide - ab71689 from Abcam Category Peptide

Desmoplakin (aa 1546-1558) blocking peptide - GTX88028-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

Desmoplakin (aa 1672 -1684) blocking peptide - GTX88029-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

Human DSP protein - orb246331 from Biorbyt Category Protein Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

Human DSP protein - orb246903 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Desmoplakin Peptide - AC21-2228-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Desmoplakin Peptide - AC21-2229-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DSP Peptide - 42-802P from ProSci Category Peptide

DSP Peptide - 42-801P from ProSci Category Peptide Species Human

DSP fusion protein - ag18065 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DSP, GST-tagged - DSP-12182H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Desmoplakin (DSP) - RPC203Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Desmoplakin (DSP) - RPC203Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Desmoplakin(DSP) ,partial - CSB-YP007208HU CSB-BP007208HU CSB-MP007208HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Desmoplakin(DSP) ,partial - CSB-EP007208HU from Cusabio Category Protein Source Yeast Species Human

Desmoplakin Protein (Recombinant) - abx166460 from Abbexa Category Protein Source Human Species Human

Desmoplakin, Peptide - MBS428581 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

Desmoplakin, Peptide - MBS427343 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine

Desmoplakin Recombinant Protein Antigen - NBP2-49158PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

DSP Recombinant Protein (OPCA01573) - OPCA01573 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

DSP Recombinant Protein (OPCA02644) - OPCA02644 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Desmoplakin Recombinant Protein Antigen - NBP2-48836PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Recombinant Desmoplakin (DSP) - RPU51172 from Biomatik Category Protein Prices $167.00, $342.00, $523.00, $653.60 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

DSP Recombinant Protein (OPCD02810) - OPCD02810 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant human Desmoplakin - AP70248 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Search more