SLC40A1

Gene Symbol	SLC40A1
Entrez Gene	30061
Alt Symbol	FPN1, HFE4, IREG1, MST079, MSTP079, MTP1, SLC11A3
Species	Human
Gene Type	protein-coding
Description	solute carrier family 40 (iron-regulated transporter), member 1
Other Description	iron regulated gene 1|putative ferroportin 1 variant IIIA|putative ferroportin 1 variant IIIB|solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3|solute carrier family 40 member 1
Swissprots	Q9NRL0 Q7Z4F8 Q8IVB2 Q6FI62 Q9NP59
Accessions	AAX93082 CAE53170 CAE81347 CAE81348 CAE83578 CAI45360 CBM40849 EAX10901 EAX10902 Q9NP59 AF147322 AF171087 AAQ13603 AF215636 AAF80986 AF226614 AAF36697 AF231121 AAF44330 AK002038 BAA92049 AK223236 BAD96956 AK292146 BAF84835 AK314827 BAG37348 AL136944 CAB66878 AM393277 CAL38155 BC035893 AAH35893 BC037733 AAH37733 BX537503 CR533564 CAG38595 DA806565 DQ065759 AAY78556 DQ065760 AAY78557 DQ065761 AAY78558 DQ065762 AAY78559 DQ065763 AAY78560 DQ065764 AAY78561 DQ890880 ABM81806 DQ894034 ABM84960 XM_005246505 XP_005246562 NM_014585 NP_055400
Function	May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
Subcellular Location	Cell membrane {ECO:0000269|PubMed:10882071, ECO:0000269|PubMed:23219802}; Multi-pass membrane protein {ECO:0000269|PubMed:10882071, ECO:0000269|PubMed:23219802}. Note=Localized to the basolateral membrane of polarized epithelial cells.
Tissue Specificity	Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen. {ECO:0000269|PubMed:10747949, ECO:0000269|PubMed:23219802}.
Top Pathways	Mineral absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC40A1 full length protein - ab153316 from Abcam Category Protein Source Wheat germ Species Human

Human SLC40A1 peptide - ab97416 from Abcam Category Peptide

SLC40A1 / Ferroportin-1 Antibody Blocking Peptide - LS-E16154 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Ferroportin/SLC40A1 Recombinant Protein - H00030061-P01 from Novus Biologicals Category Protein

SLC40A1-Antibody-C-term-Blocking-Peptide - BP17042b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC40A1 Blocking Peptide - 33R-3575 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Ferroportin Protein - abx066553 from Abbexa Category Protein Source E.coli Species Human

MTP1 - H00030061-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

MTP1 - H00030061-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

MTP1 - H00030061-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

Ferroportin (FPN), Human - 20-8502 from ARP American Research Products Category Protein Prices $419.00 Sizes 50 µg Source E.coli Species Human

SLC40A1 fusion protein - ag13573 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Native Human Solute Carrier Family 40 (iron-regulated transporter), Member 1 - SLC40A1-5335H from Creative Biomart Category Protein Source Human spleen Species Human

Recombinant Ferroportin (FPN) - RPC489Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Ferroportin (FPN) - RPC489Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Ferroportin (FPN) - RPC489Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Ferroportin (FPN) - RPC489Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Ferroportin (FPN) - RPC489Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Ferroportin/SLC40A1 Blocking Peptide - NBP1-21502PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Ferroportin/SLC40A1 Recombinant Protein Antigen - NBP2-49454PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

SLC40A1 Peptide, Human - M34GP14573H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ferroportin (FPN), Recombinant Protein - MBS2012282 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli

SLC40A1 Recombinant Protein (OPCD03303) - OPCD03303 from Aviva Systems Biology Category Protein Source E.coli Species Human

Solute carrier family 40 member 1 (SLC40A1), Recombinant Protein - MBS7098820 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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