SLC40A1

Gene Symbol SLC40A1
Entrez Gene 30061
Alt Symbol FPN1, HFE4, IREG1, MST079, MSTP079, MTP1, SLC11A3
Species Human
Gene Type protein-coding
Description solute carrier family 40 (iron-regulated transporter), member 1
Other Description iron regulated gene 1|putative ferroportin 1 variant IIIA|putative ferroportin 1 variant IIIB|solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3|solute carrier family 40 member 1
Swissprots Q9NRL0 Q7Z4F8 Q8IVB2 Q6FI62 Q9NP59
Accessions AAX93082 CAE53170 CAE81347 CAE81348 CAE83578 CAI45360 CBM40849 EAX10901 EAX10902 Q9NP59 AF147322 AF171087 AAQ13603 AF215636 AAF80986 AF226614 AAF36697 AF231121 AAF44330 AK002038 BAA92049 AK223236 BAD96956 AK292146 BAF84835 AK314827 BAG37348 AL136944 CAB66878 AM393277 CAL38155 BC035893 AAH35893 BC037733 AAH37733 BX537503 CR533564 CAG38595 DA806565 DQ065759 AAY78556 DQ065760 AAY78557 DQ065761 AAY78558 DQ065762 AAY78559 DQ065763 AAY78560 DQ065764 AAY78561 DQ890880 ABM81806 DQ894034 ABM84960 XM_005246505 XP_005246562 NM_014585 NP_055400
Function May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
Subcellular Location Cell membrane {ECO:0000269|PubMed:10882071, ECO:0000269|PubMed:23219802}; Multi-pass membrane protein {ECO:0000269|PubMed:10882071, ECO:0000269|PubMed:23219802}. Note=Localized to the basolateral membrane of polarized epithelial cells.
Tissue Specificity Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen. {ECO:0000269|PubMed:10747949, ECO:0000269|PubMed:23219802}.
Top Pathways Mineral absorption

Ferroportin-1 CRISPR/Cas9 KO Plasmid (h) - sc-400872 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 HDR Plasmid (h) - sc-400872-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 Double Nickase Plasmid (h) - sc-400872-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 Double Nickase Plasmid (h2) - sc-400872-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 CRISPR Activation Plasmid (h) - sc-400872-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 CRISPR Activation Plasmid (h2) - sc-400872-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 Lentiviral Activation Particles (h) - sc-400872-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 Lentiviral Activation Particles (h2) - sc-400872-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 siRNA (h) - sc-60633 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ferroportin-1 shRNA Plasmid (h) - sc-60633-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ferroportin-1 shRNA (h) Lentiviral Particles - sc-60633-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ferroportin/SLC40A1 RNAi - H00030061-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU018971 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19630 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19630 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08744 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08744

SLC40A1 siRNA (Human) - CRH9336 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC40A1 - MBS8234988 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Ferroportin-1 CRISPR/Cas9 KO Plasmid (h2) - sc-400872-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ferroportin-1 HDR Plasmid (h2) - sc-400872-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human SLC40A1 (NM_014585.5) - SHH411244 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC40A1 siRNA - orb269838 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC40A1 shRNA Plasmid (Human) - CHH9336 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC40A1 miRNA 3'UTR clone - MiUTR3H-06983 from Creative biogene

Species Reactivities Human
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