IRF2BP1

Gene Symbol IRF2BP1
Entrez Gene 26145
Alt Symbol -
Species Human
Gene Type protein-coding
Description interferon regulatory factor 2 binding protein 1
Other Description IRF-2-binding protein 1|interferon regulatory factor 2-binding protein 1|probable E3 ubiquitin-protein ligase IRF2BP1
Swissprots Q9Y4P4 Q9BRZ9 Q53EL7 Q8IU81 Q6DC95
Accessions CAC43219 EAW57396 Q8IU81 AK092407 AK223622 BAD97342 AK315060 BAG37535 AL080159 CAB45750 AY278022 AAP78943 BC005834 AAH05834 BC038222 AAH38222 BC039002 AAH39002 BC078181 AAH78181 DA791039 NM_015649 NP_056464
Function Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. {ECO:0000269|PubMed:12799427, ECO:0000269|PubMed:18671972}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12799427}.

IRF-2BP1 (A-10) - sc-373899 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IRF-2BP1 (A-10): sc-373899. Western blot analysis of IRF-2BP1 expression in non-transfected: sc-117752 (A) and human IRF-2BP1 transfected: sc-111584 (B) 293T whole cell lysates.

IRF-2BP1 (D-15) - sc-161743 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IRF-2BP1 (D-15): sc-161743. Western blot analysis of IRF-2BP1 expression in HeLa whole cell lysate.

IRF-2BP1 (G-14) - sc-161744 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IRF-2BP1 (G-14): sc-161744. Western blot analysis of IRF-2BP1 expression in non-transfected: sc-117752 (A) and human IRF-2BP1 transfected: sc-111584 (B) 293T whole cell lysates.

IRF-2BP1 (T-14) - sc-161745 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IRF-2BP1 (T-14): sc-161745. Western blot analysis of IRF-2BP1 expression in non-transfected: sc-117752 (A) and human IRF-2BP1 transfected: sc-111584 (B) 293T whole cell lysates.

Anti-IRF2BP1 antibody - ab68956 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-IRF2BP1 antibody (ab68956) at 1/500 dilutionLane 1 : IRF2BP1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

Anti-IRF2BP1 Antibody - LS-C308518 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-IRF2BP1 Antibody (aa178-227) - LS-C135339 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IRF2BP1 antibody LS-C135339 Western blot of Rat Liver lysate. Antibody concentration 1 ug/ml.

Anti-IRF2BP1 Antibody (aa468-517) - LS-C102613 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IRF2BP1 antibody LS-C102613 Western blot of Placenta lysate.

Anti-IRF2BP1 Antibody (aa109-122) - LS-C139734 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
IRF2BP1 antibody (0.1 ug/ml) staining of HepG2 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-IRF2BP1 Antibody (aa450-500) - LS-C289884 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human IRF2BP1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), Jurkat (J; 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-IRF2BP1 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. IRF2BP1 was also immunoprecipitated by rabbit anti-IRF2BP1 antibody BL11357, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

Anti-IRF2BP1 Antibody (aa461-474) - LS-C139735 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
IRF2BP1 antibody (0.5 ug/ml) staining of Human Liver lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IRF2BP1 Antibody - AF6800 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of Jurkat human acute T cell leukemia cell line, HepG2 human hepatocellular carcinoma cell line, and MOLT‑4 human acute lymphoblastic leukemia cell line untreated (-) or treated (+) with 10 ng/mL Recombinant Human TGF‑ beta 1 (Catalog # 240-B) for 2 hours. Gels were loaded with 30 µg of whole cell lysate (WCL) and 10 µg of nuclear extracts (Nuc). PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human IRF2BP1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6800) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for IRF2BP1 at approximately 70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

IRF2BP1 Antibody - NBP1-55309 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IRF2BP1 Antibody [NBP1-55309] - Human Placenta lysate, concentration 0.2-1 ug/ml.

IRF2BP1 Antibody - NBP2-14127 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IRF2BP1 Antibody [NBP2-14127] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Human cell line RT-4Lane 3: Human cell line U-251MG sp

IRF2BP1 Antibody - NBP1-72005 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: IRF2BP1 Antibody [NBP1-72005] - Analysis of anti-IRF2BP1 antibody with human placenta at concentration 5 ug/ml.

IRF2BP1 Antibody - H00026145-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-IRF2BP1 antibody produced in goat - SAB2501527 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IRF2BP1 <B>Cat. No. SAB2501527</B>: (0.5 μg/mL) staining of Human Liver lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-IRF2BP1 antibody produced in rabbit - SAB2101175 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IRF2BP1: <B>Cat. No.SAB2101175</B>: IRF2BP1 in Placenta tissue lysate with IRF2BP1 antibody at 1.0 μg/mL.

Anti-IRF2BP1 antibody produced in mouse - SAB1407286 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IRF2BP1: <B>Cat. No. SAB1407286</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~64.2 kDa using IRF2BP1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-IRF2BP1 antibody produced in rabbit - HPA042164 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IRF2BP1:<B>Cat. No. HPA042164</B>: Immunohistochemical staining of human pancreas shows strong nuclear positivity in exocrine glandular cells and islets of Langerhans.

Anti-IRF2BP1 antibody produced in goat - SAB2501770 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IRF2BP1: <B>Cat. No. SAB2501770</B>: (0.1 μg/mL) staining of HepG2 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IRF2BP1 antibody - middle region (ARP55315_P050) - ARP55315_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IRF2BP1-aa461-474-Antibody-internal-region - AF3456a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3456a (1 µg/ml) staining of nuclear NIH3T3 lysate (A) and of Mouse (B) and Rat (C) Colon lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IRF2BP1-aa109-122-Antibody-internal-region - AF3455a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3455a (0.1 µg/ml) staining of HepG2 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IRF2BP1 antibody - GTX49123 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
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