Gene Symbol | IRF2BP1 |
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Entrez Gene | 26145 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | interferon regulatory factor 2 binding protein 1 |
Other Description | IRF-2-binding protein 1|interferon regulatory factor 2-binding protein 1|probable E3 ubiquitin-protein ligase IRF2BP1 |
Swissprots | Q9Y4P4 Q9BRZ9 Q53EL7 Q8IU81 Q6DC95 |
Accessions | CAC43219 EAW57396 Q8IU81 AK092407 AK223622 BAD97342 AK315060 BAG37535 AL080159 CAB45750 AY278022 AAP78943 BC005834 AAH05834 BC038222 AAH38222 BC039002 AAH39002 BC078181 AAH78181 DA791039 NM_015649 NP_056464 |
Function | Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. {ECO:0000269|PubMed:12799427, ECO:0000269|PubMed:18671972}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12799427}. |
IRF-2BP1 CRISPR/Cas9 KO Plasmid (h) - sc-409876 from Santa Cruz Biotechnology
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IRF-2BP1 HDR Plasmid (h) - sc-409876-HDR from Santa Cruz Biotechnology
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IRF-2BP1 Double Nickase Plasmid (h) - sc-409876-NIC from Santa Cruz Biotechnology
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IRF-2BP1 Double Nickase Plasmid (h2) - sc-409876-NIC-2 from Santa Cruz Biotechnology
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IRF-2BP1 CRISPR Activation Plasmid (h) - sc-409876-ACT from Santa Cruz Biotechnology
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IRF-2BP1 CRISPR Activation Plasmid (h2) - sc-409876-ACT-2 from Santa Cruz Biotechnology
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IRF-2BP1 Lentiviral Activation Particles (h) - sc-409876-LAC from Santa Cruz Biotechnology
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IRF-2BP1 Lentiviral Activation Particles (h2) - sc-409876-LAC-2 from Santa Cruz Biotechnology
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IRF-2BP1 siRNA (h) - sc-97273 from Santa Cruz Biotechnology
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IRF-2BP1 shRNA Plasmid (h) - sc-97273-SH from Santa Cruz Biotechnology
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IRF-2BP1 shRNA (h) Lentiviral Particles - sc-97273-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU120681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10763 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10763 from Sigma-Aldrich
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IRF2BP1 siRNA (Human) - CRH8729 from Cohesion Biosciences
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IRF2BP1 - MBS8220084 from MyBioSource
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shRNA set against Human IRF2BP1 (NM_015649.1) - SHH320581 from Creative biogene
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shRNA set against Human IRF2BP1(NM_015649.1) - SHL173718 from Creative biogene
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IRF2BP1 shRNA Plasmid (Human) - CHH8729 from Cohesion Biosciences
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IRF2BP1 miRNA 3'UTR clone - MiUTR1H-04991 from Creative biogene
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