| Gene Symbol |
IRF2BP1
|
| Entrez Gene |
26145
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interferon regulatory factor 2 binding protein 1
|
| Other Description |
IRF-2-binding protein 1|interferon regulatory factor 2-binding protein 1|probable E3 ubiquitin-protein ligase IRF2BP1
|
| Swissprots |
Q9Y4P4 Q9BRZ9 Q53EL7 Q8IU81 Q6DC95
|
| Accessions |
CAC43219 EAW57396 Q8IU81 AK092407 AK223622 BAD97342 AK315060 BAG37535 AL080159 CAB45750 AY278022 AAP78943 BC005834 AAH05834 BC038222 AAH38222 BC039002 AAH39002 BC078181 AAH78181 DA791039 NM_015649 NP_056464
|
| Function |
Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. {ECO:0000269|PubMed:12799427, ECO:0000269|PubMed:18671972}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:12799427}.
|