Gene Symbol | LBP |
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Entrez Gene | 3929 |
Alt Symbol | BPIFD2 |
Species | Human |
Gene Type | protein-coding |
Description | lipopolysaccharide binding protein |
Other Description | BPI fold containing family D, member 2|LPS-binding protein|lipopolysaccharide-binding protein |
Swissprots | Q9H403 P18428 Q9UD66 O43438 Q92672 B2R938 |
Accessions | AAA66446 AAC39547 CAA67226 CAC10462 EAW76033 EAW76034 P18428 AF105067 AAD21962 AK313625 BAG36385 AY344471 AAR03787 BC022256 AAH22256 BQ028088 DQ891394 ABM82320 DQ894434 ABM85360 M35533 AAA59493 NM_004139 NP_004130 |
Function | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide. {ECO:0000269|PubMed:17481951, ECO:0000269|PubMed:24120359}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:24120359}. |
Tissue Specificity | Detected in blood serum (at protein level). {ECO:0000269|PubMed:24120359}. |
Top Pathways | Toll-like receptor signaling pathway, Salmonella infection, Tuberculosis |
LBP (N-17) - sc-14666 from Santa Cruz Biotechnology
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LBP (K-15) - sc-14668 from Santa Cruz Biotechnology
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LBP (H-117) - sc-292421 from Santa Cruz Biotechnology
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Anti-LBP antibody - ab25094 from Abcam
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Anti-LBP antibody - ab96748 from Abcam
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Anti-LBP antibody [EPR10865] - ab169776 from Abcam
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Anti-LBP Antibody - LS-C8493 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C8491 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C8494 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C123980 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C123981 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C125880 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C125879 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C125881 from LifeSpan Bioscience
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Anti-LBP Antibody (aa26-478) - LS-C130466 from LifeSpan Bioscience
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Anti-LBP Antibody (clone M330-19) - LS-C139859 from LifeSpan Bioscience
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Anti-LBP Antibody (clone RR433-8) - LS-C139860 from LifeSpan Bioscience
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Anti-LBP Antibody (clone 6G3) - LS-C139977 from LifeSpan Bioscience
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Anti-LBP Antibody (clone 1C7) - LS-C139978 from LifeSpan Bioscience
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Anti-LBP Antibody - LS-C140240 from LifeSpan Bioscience
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Anti-LBP Antibody (aa63-74) - LS-C147974 from LifeSpan Bioscience
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Anti-LBP Antibody (clone M300-19) - LS-C202482 from LifeSpan Bioscience
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Anti-LBP Antibody (aa221-270) - LS-C291462 from LifeSpan Bioscience
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Anti-LBP Antibody (aa27-481) - LS-C295182 from LifeSpan Bioscience
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Anti-LBP Antibody (clone 4E8) - LS-C197604 from LifeSpan Bioscience
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