Gene Symbol | CBR4 |
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Entrez Gene | 84869 |
Alt Symbol | SDR45C1 |
Species | Human |
Gene Type | protein-coding |
Description | carbonyl reductase 4 |
Other Description | 3-oxoacyl-[acyl-carrier-protein] reductase|carbonic reductase 4|carbonyl reductase family member 4|quinone reductase CBR4|short chain dehydrogenase/reductase family 45C member 1|short chain dehydrogenase/reductase family 45C, member 1 |
Swissprots | Q8WTW8 Q8N4T8 Q96K93 |
Accessions | CBF61666 CBU86558 EAX04797 EAX04798 Q8N4T8 AK027337 BAB55045 AK291756 BAF84445 AL049442 AL833393 CAH10582 AV704400 BC021973 AAH21973 BC033650 AAH33650 BG119539 BQ230058 DA217727 HQ447088 ADQ31575 W70279 XM_005263315 XP_005263372 XM_005263316 XP_005263373 XM_006714391 XP_006714454 XM_006714392 XP_006714455 XM_011532385 XP_011530687 XM_011532386 XP_011530688 XR_938789 NM_032783 NP_116172 |
Function | The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). {ECO:0000269|PubMed:19000905, ECO:0000269|PubMed:19571038}. |
Subcellular Location | Mitochondrion matrix {ECO:0000269|PubMed:19000905, ECO:0000269|PubMed:19571038}. |
Tissue Specificity | Detected in liver and kidney (at protein level). {ECO:0000269|PubMed:19000905}. |
Human CBR4 full length protein - ab101110 from Abcam
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CBR4 Antibody Blocking Peptide - LS-E5092 from LifeSpan Bioscience
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CBR4 Antibody Blocking Peptide - LS-E22196 from LifeSpan Bioscience
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CBR4 Antibody Blocking Peptide - LS-E22197 from LifeSpan Bioscience
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CBR4 Recombinant Protein - H00084869-P01 from Novus Biologicals
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Recombinant Human CBR4 Protein - NBP1-50867 from Novus Biologicals
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CBR4-Antibody-C-term-Blocking-Peptide - BP17512b from Abgent, a WuXi AppTec company
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CBR4 Protein (OPPA02528) - OPPA02528 from Aviva Systems Biology
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Human CBR4 protein - orb168044 from Biorbyt
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CBR4 Blocking Peptide - 33R-9553 from Fitzgerald
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CBR4 Blocking Peptide - 33R-7994 from Fitzgerald
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CBR4 protein (His tag) - 80R-1542 from Fitzgerald
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Carbonyl reductase 4 (1-237, His-tag) - AR09720PU-L from Acris Antibodies
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Carbonyl reductase 4 (1-237, His-tag) - AR09720PU-N from Acris Antibodies
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Carbonyl reductase 4 - H00084869-P01 from Acris Antibodies
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Carbonyl Reductase-4, Human Recombinant - 228-12178-1 from RayBiotech
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CBR4, 1-237aa, Human, His tag, E.coli - 01-2396-4 from ARP American Research Products
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CBR4 fusion protein - ag4678 from Proteintech Group
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CBR4 Human - ENPS-029 from NeoScientific
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Recombinant Human Carbonyl Reductase-4 - BP000869-ENZ-022 from Syd Labs
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CBR4, 1-237aa, Recombinant Protein - GWB-P1257I from Genway Biotech
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CBR4 Human Protein - GWB-BSP145 from Genway Biotech
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Recombinant Human CBR4, His-tagged - CBR4-2876H from Creative Biomart
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Recombinant Human CBR4, His-tagged - CBR4-26329TH from Creative Biomart
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CBR4 - JNV-033 from Reagent Proteins
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