PTK2

Gene Symbol PTK2
Entrez Gene 396416
Alt Symbol FAK, FRNK, p125FAK
Species Chicken
Gene Type protein-coding
Description protein tyrosine kinase 2
Other Description FADK 1|PTK2 protein tyrosine kinase 2|focal adhesion kinase 1|focal adhesion kinase-related nonkinase|p41/p43FRNK|pp125FAK|protein-tyrosine kinase 2
Swissprots Q00944
Accessions Q00944 L07415 AAA48773 L08402 AAA48766 M86656 AAA48765 NM_205435 NP_990766
Function Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development, embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), ephrin receptors, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, cre
Subcellular Location Cell junction, focal adhesion {ECO:0000269|PubMed:8423801}. Cell membrane {ECO:0000269|PubMed:8423801}; Peripheral membrane protein {ECO:0000269|PubMed:8423801}; Cytoplasmic side {ECO:0000269|PubMed:8423801}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:8423801}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Nucleus {ECO:0000269|PubMed:8423801}. Note=Constituent of focal adhesions. Detected at microtubules (By similarity). {ECO:0000250}.
Top Pathways VEGF signaling pathway, Focal adhesion, ErbB signaling pathway, Regulation of actin cytoskeleton

Focal adhesion kinase 1 (PTK2), Chicken, ELISA Kit - CSB-EL018993CH from ARP American Research Products

Category ELISA Kit
Prices $550.00, $790.00, $791.00, $794.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Focal adhesion kinase 1, PTK2, Chicken, ELISA Kit - E1178c from ARP American Research Products

Category ELISA Kit
Prices $796.00
Sizes 96 t

Chicken FAK (Focal Adhesion Kinase) ELISA Kit - E-EL-Ch0133 from Elabscience

Category ELISA Kit
Range ~

Chicken Focal adhesion kinase 1(PTK2) ELISA kit - CSB-EL018993CH from Cusabio

Category ELISA Kit
Sensitivity Request Information
Range Request Information

PTK2 protein tyrosine kinase 2, ELISA Kit - MBS922799 from MyBioSource

Category ELISA Kit
Prices $550.00, $795.00, $2,890.00, $5,465.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chicken FAK (Focal Adhesion Kinase) ELISA Kit - E-EL-Ch0133 from Iwai North America Inc.

Category ELISA Kit
Prices $722.50
Sizes 1 kit
Sensitivity N/A

Chicken Focal adhesion kinase 1 (PTK2) ELISA Kit - EKC31920 from Biomatik

Category ELISA Kit
Prices $795.00, $3,021.00, $5,645.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 11.72 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Chicken PTK2 ELISA Kit - E083101 from Biobool

Category ELISA Kit

Focal adhesion kinase 1, ELISA Kit - MBS2881625 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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