Gene Symbol | BLOC1S3 |
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Entrez Gene | 388552 |
Alt Symbol | BLOS3, HPS8, RP |
Species | Human |
Gene Type | protein-coding |
Description | biogenesis of lysosomal organelles complex-1, subunit 3 |
Other Description | BLOC-1 subunit 3|biogenesis of lysosome-related organelles complex 1 subunit 3|biogenesis of lysosome-related organelles complex-1, subunit 3|reduced pigmentation, mouse, homolog of |
Swissprots | B2RXB8 Q6QNY0 |
Accessions | Q6QNY0 AK130151 AK130186 BAC85300 AK296695 BAG59289 AY531266 AAT00462 BC151151 AAI51152 BC151152 AAI51153 BU616355 DC422050 DN996082 LN608738 XM_011526952 XP_011525254 XR_935826 XR_935827 XR_935828 XR_935829 NM_212550 NP_997715 |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:16385460, ECO:0000269|PubMed:17182842}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
BLOS3 (C-12) - sc-167211 from Santa Cruz Biotechnology
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BLOS3 (T-13) - sc-167213 from Santa Cruz Biotechnology
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Anti-BLOC1S3 antibody - C-terminal - ab156160 from Abcam
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Anti-BLOC1S3 Antibody (aa176-202, AP) - LS-C233165 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202, APC) - LS-C233167 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202, Biotin) - LS-C233168 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202, FITC) - LS-C233169 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202, Azide-free, HRP) - LS-C249527 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202, PE) - LS-C233171 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202) - LS-C319846 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa48-97) - LS-C151936 from LifeSpan Bioscience
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Anti-BLOC1S3 Antibody (aa176-202) - LS-C157582 from LifeSpan Bioscience
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BLOS3 Antibody - NBP1-98303 from Novus Biologicals
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ANTI-BLOC1S3(C-TERMINAL) antibody produced in rabbit - SAB1305951 from Sigma-Aldrich
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BLOC1S3 antibody - N-terminal region (ARP65298_P050) - ARP65298_P050 from Aviva Systems Biology
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BLOC1S3-Antibody-C-term - AP19902b from Abgent, a WuXi AppTec company
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) - 032534 from USBiological Life Science
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) (AP) - 032534-AP from USBiological Life Science
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) (APC) - 032534-APC from USBiological Life Science
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) (Azide free) (HRP) - 032534-HRP from USBiological Life Science
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) (Biotin) - 032534-Biotin from USBiological Life Science
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) (FITC) - 032534-FITC from USBiological Life Science
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Anti -BLOC1S3, CT (BLOC1S3, BLOS3, Biogenesis of lysosome-related organelles complex 1subunit 3) (PE) - 032534-PE from USBiological Life Science
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BLOC1S3 Antibody - C-terminal region (OAAB15354) - OAAB15354 from Aviva Systems Biology
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BLOC1S3 Antibody - abx031279 from Abbexa
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