Gene Symbol | BLOC1S3 |
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Entrez Gene | 388552 |
Alt Symbol | BLOS3, HPS8, RP |
Species | Human |
Gene Type | protein-coding |
Description | biogenesis of lysosomal organelles complex-1, subunit 3 |
Other Description | BLOC-1 subunit 3|biogenesis of lysosome-related organelles complex 1 subunit 3|biogenesis of lysosome-related organelles complex-1, subunit 3|reduced pigmentation, mouse, homolog of |
Swissprots | B2RXB8 Q6QNY0 |
Accessions | Q6QNY0 AK130151 AK130186 BAC85300 AK296695 BAG59289 AY531266 AAT00462 BC151151 AAI51152 BC151152 AAI51153 BU616355 DC422050 DN996082 LN608738 XM_011526952 XP_011525254 XR_935826 XR_935827 XR_935828 XR_935829 NM_212550 NP_997715 |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:16385460, ECO:0000269|PubMed:17182842}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
BLOC1S3 Antibody Blocking Peptide - LS-E23770 from LifeSpan Bioscience
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Recombinant Human BLOC1S3 - BLOC1S3-952H from Creative Biomart
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Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 3(BLOC1S3) - CSB-YP747525HU CSB-EP747525HU CSB-BP747525HU CSB-MP747525HU from Cusabio
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Biogenesis of lysosomal organelles complex-1, subunit 3 (BLOC1S3) - TP321221 from Acris Antibodies
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BLOC1S3 fusion protein - Ag22801 from Proteintech Group
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BLOC1S3-Blocking-Peptide-C-term - BP19902B from Abgent, a WuXi AppTec company
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BLOC1S3 Peptide, Human - M34GP01459H from Creative Peptides
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Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC1S3), Recombinant Protein - MBS1447749 from MyBioSource
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BLOS3 Recombinant Protein Antigen - NBP2-55573PEP from Novus Biologicals
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