Gene Symbol | ERVFRD-1 |
---|---|
Entrez Gene | 405754 |
Alt Symbol | ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, UNQ6191, envFRD |
Species | Human |
Gene Type | protein-coding |
Description | endogenous retrovirus group FRD, member 1 |
Other Description | HERV-FRD provirus ancestral Env polyprotein|HERV-FRD_6p24.1 provirus ancestral Env polyprotein|endogenous retrovirus group FRD member 1|envelope polyprotein|syncytin 2|syncytin-2 |
Swissprots | P60508 |
Accessions | CAH68778 P60508 AK075092 BAC11396 AK123938 BAC85731 AY358244 AAQ88611 BC068585 AAH68585 DA863475 GQ129285 ACT64419 GQ129286 ACT64420 NM_207582 NP_997465 |
Function | This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732). {ECO:0000269|PubMed:18988732}. |
Subcellular Location | Virion {ECO:0000305}. |
Tissue Specificity | Expressed at higher level in placenta. Expressed at lower level in adrenal, bone marrow, brain, breast, colon, kidney, lung, ovary, peripheral blood lymphocytes, prostate, skin, spleen, testis, thymus, thyroid, trachea. {ECO:0000269|PubMed:12970426}. |
Human HERV-FRD full length protein - ab166518 from Abcam
|
||||||||||
ERVFRD-1 / HERV-FRD Antibody Blocking Peptide - LS-E2117 from LifeSpan Bioscience
|
||||||||||
ERVFRD-1 / HERV-FRD Antibody Blocking Peptide - LS-E20286 from LifeSpan Bioscience
|
||||||||||
Recombinant Human ERVFRD-1 Protein - H00405754-P01 from Novus Biologicals
|
||||||||||
HERV-FRD-Antibody-N-term-Blocking-peptide - BP13018a from Abgent, a WuXi AppTec company
|
||||||||||
HERV-FRD Blocking Peptide - 33R-9095 from Fitzgerald
|
||||||||||
ERVFRDE1 / HERV-FRD - H00405754-P01 from Acris Antibodies
|
||||||||||
HERV-FRD fusion protein - ag12380 from Proteintech Group
|
||||||||||
Recombinant Human HERV-FRD_6p24.1 provirus ancestral Env polyprotein(ERVFRD-1) - CSB-YP352689HU CSB-EP352689HU CSB-BP352689HU CSB-MP352689HU from Cusabio
|
||||||||||
ERVFRD-1 Peptide, Human - M34GP05068H from Creative Peptides
|
||||||||||
HERV-FRD_6p24.1 provirus ancestral Env polyprotein (ERVFRD-1), Recombinant Protein - MBS1020059 from MyBioSource
|