CHST8

Gene Symbol CHST8
Entrez Gene 64377
Alt Symbol GALNAC4ST1, GalNAc4ST, PSS3
Species Human
Gene Type protein-coding
Description carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
Other Description GALNAC-4-ST1|GalNAc-4-O-sulfotransferase 1|N-acetylgalactosamine-4-O-sulfotransferase 1|carbohydrate sulfotransferase 8|galNAc4ST-1
Swissprots Q9H2A9 Q9H3N2
Accessions Q9H2A9 AB047801 BAB19806 AF300612 AAG39444 AF305781 AAL09373 BC011380 AAH11380 BC014250 AAH14250 BC018723 AAH18723 BI917117 BX354555 DB500322 DQ891438 ABM82364 DQ894614 ABM85540 XM_011527220 XP_011525522 XM_011527221 XP_011525523 XM_011527222 XP_011525524 XM_011527223 XP_011525525 XM_011527224 XP_011525526 XM_011527225 XP_011525527 XM_011527226 XP_011525528 NM_001127895 NP_001121367 NM_001127896 NP_001121368 NM_022467 NP_071912
Function Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. {ECO:0000269|PubMed:10988300, ECO:0000269|PubMed:11445554}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Predominantly expressed in pituitary gland. In brain, it is expressed in pituitary gland, cerebellum, medulla oblongata, pons, thalamus and spinal cord. Expressed in the epidermis. Expressed at lower level in lung, spleen, adrenal gland, placenta, prostate, testis, mammary gland and trachea. {ECO:0000269|PubMed:10988300, ECO:0000269|PubMed:11001942, ECO:0000269|PubMed:11445554, ECO:0000269|PubMed:22289416}.

GALNAC4ST1 / CHST8 Antibody Blocking Peptide - LS-E1985 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GALNAC4ST1 / CHST8 Antibody Blocking Peptide - LS-E17952 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CHST8-Antibody-Center-Blocking-peptide - BP12842c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CHST8 Blocking Peptide - 33R-3192 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CHST8 fusion protein - ag9669 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Carbohydrate sulfotransferase 8(CHST8) - CSB-YP872476HU CSB-EP872476HU CSB-BP872476HU CSB-MP872476HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CHST8 Recombinant Protein Antigen - NBP1-83396PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CHST8 Peptide, Human - M34GP03157H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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