CHST8

Gene Symbol CHST8
Entrez Gene 64377
Alt Symbol GALNAC4ST1, GalNAc4ST, PSS3
Species Human
Gene Type protein-coding
Description carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
Other Description GALNAC-4-ST1|GalNAc-4-O-sulfotransferase 1|N-acetylgalactosamine-4-O-sulfotransferase 1|carbohydrate sulfotransferase 8|galNAc4ST-1
Swissprots Q9H2A9 Q9H3N2
Accessions Q9H2A9 AB047801 BAB19806 AF300612 AAG39444 AF305781 AAL09373 BC011380 AAH11380 BC014250 AAH14250 BC018723 AAH18723 BI917117 BX354555 DB500322 DQ891438 ABM82364 DQ894614 ABM85540 XM_011527220 XP_011525522 XM_011527221 XP_011525523 XM_011527222 XP_011525524 XM_011527223 XP_011525525 XM_011527224 XP_011525526 XM_011527225 XP_011525527 XM_011527226 XP_011525528 NM_001127895 NP_001121367 NM_001127896 NP_001121368 NM_022467 NP_071912
Function Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. {ECO:0000269|PubMed:10988300, ECO:0000269|PubMed:11445554}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Predominantly expressed in pituitary gland. In brain, it is expressed in pituitary gland, cerebellum, medulla oblongata, pons, thalamus and spinal cord. Expressed in the epidermis. Expressed at lower level in lung, spleen, adrenal gland, placenta, prostate, testis, mammary gland and trachea. {ECO:0000269|PubMed:10988300, ECO:0000269|PubMed:11001942, ECO:0000269|PubMed:11445554, ECO:0000269|PubMed:22289416}.

GalNAc4ST-1 CRISPR/Cas9 KO Plasmid (h) - sc-413006 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 HDR Plasmid (h) - sc-413006-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 Double Nickase Plasmid (h) - sc-413006-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 Double Nickase Plasmid (h2) - sc-413006-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 CRISPR Activation Plasmid (h) - sc-413006-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 CRISPR Activation Plasmid (h2) - sc-413006-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 Lentiviral Activation Particles (h) - sc-413006-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 Lentiviral Activation Particles (h2) - sc-413006-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GalNAc4ST-1 siRNA (h) - sc-60691 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GalNAc4ST-1 shRNA Plasmid (h) - sc-60691-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GalNAc4ST-1 shRNA (h) Lentiviral Particles - sc-60691-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU006621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6116 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6116 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CHST8 siRNA (Human) - CRJ1997 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHST8 - MBS8202721 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHST8 (NM_022467.3) - SHH263853 from Creative biogene

Category siRNA
Species Reactivities Human

Human CHST8 siRNA - orb272498 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHST8 shRNA Plasmid (Human) - CHJ1997 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHST8 miRNA 3'UTR clone - MiUTR1H-02153 from Creative biogene

Species Reactivities Human

CHST8 miRNA 3'UTR clone - MiUTR3H-11075 from Creative biogene

Species Reactivities Human

CHST8 miRNA 3'UTR clone - MiUTR3H-11076 from Creative biogene

Species Reactivities Human
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