Hsd11b1

Gene Symbol Hsd11b1
Entrez Gene 100135542
Alt Symbol -
Species Guinea Pig
Gene Type protein-coding
Description hydroxysteroid 11-beta dehydrogenase 1
Other Description 11-DH|11-beta-HSD1|11-beta-hydroxysteroid dehydrogenase 1|11-beta-hydroxysteroid dehydrogenase type 1|corticosteroid 11-beta-dehydrogenase isozyme 1|hydroxysteroid (11-beta) dehydrogenase 1
Swissprots Q9QZE1 Q6QLL4
Accessions Q6QLL4 AF188005 AAF01249 AY535424 AAS47491 NM_001172857 NP_001166328
Function Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:10699594}; Single-pass type II membrane protein {ECO:0000269|PubMed:10699594}.
Tissue Specificity Widely expressed at low levels. Highest expression in liver. {ECO:0000269|PubMed:10699594}.

Anti-HSD11B1 antibody - ab83522 from Abcam

Prices $400.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HSD11B1 antibody (ab83522) at 1 µg/ml (in 5% skim milk/ PBS) + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-HSD11B1 antibody [EP9406(2)] - ab169785 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP9406(2)
All lanes : Anti-HSD11B1 antibody [EP9406(2)] (ab169785) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : Raji lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution
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