Gene Symbol | Hsd11b1 |
---|---|
Entrez Gene | 100135542 |
Alt Symbol | - |
Species | Guinea Pig |
Gene Type | protein-coding |
Description | hydroxysteroid 11-beta dehydrogenase 1 |
Other Description | 11-DH|11-beta-HSD1|11-beta-hydroxysteroid dehydrogenase 1|11-beta-hydroxysteroid dehydrogenase type 1|corticosteroid 11-beta-dehydrogenase isozyme 1|hydroxysteroid (11-beta) dehydrogenase 1 |
Swissprots | Q9QZE1 Q6QLL4 |
Accessions | Q6QLL4 AF188005 AAF01249 AY535424 AAS47491 NM_001172857 NP_001166328 |
Function | Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10699594}; Single-pass type II membrane protein {ECO:0000269|PubMed:10699594}. |
Tissue Specificity | Widely expressed at low levels. Highest expression in liver. {ECO:0000269|PubMed:10699594}. |
Recombinant Guinea pig Corticosteroid 11-beta-dehydrogenase isozyme 1(HSD11B1) - CSB-YP740819GU CSB-EP740819GU CSB-BP740819GU CSB-MP740819GU from Cusabio
|
||||||||||
Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1), Recombinant Protein - MBS1302588 from MyBioSource
|