ERCC5

Gene Symbol ERCC5
Entrez Gene 2073
Alt Symbol COFS3, ERCC5-201, ERCM2, UVDR, XPG, XPGC
Species Human
Gene Type protein-coding
Description excision repair cross-complementation group 5
Other Description DNA excision repair protein ERCC-5|DNA repair protein complementing XP-G cells|XPG-complementing protein|excision repair cross-complementing rodent repair deficiency, complementation group 5|xeroderma pigmentosum, complementation group G
Swissprots Q9HD60 Q9HD59 P28715 Q8N1B7 Q5JUS5 Q8IZL6 A6NGT4 Q7Z2V3 Q5JUS4
Accessions AAF89177 AAF89178 AAF89179 AAN46091 CAA50481 EAX09071 EAX09072 P28715 AF462447 AAP97715 AK294708 BAG57863 AK299758 BAG61647 AK303558 BAG64582 BC031522 AAH31522 BE223050 BQ002437 BQ707436 BX647399 D16305 BAA03812 DA195001 DQ891818 ABM82744 DQ895006 ABM85932 L20046 AAC37533 LM994821 CDY80174 X69978 CAA49598 NM_000123 NP_000114
Function Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Subcellular Location Nucleus {ECO:0000269|PubMed:7651464}.
Top Pathways Nucleotide excision repair

XPG (8H7) - sc-13563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XPG (8H7): sc-13563. Western blot analysis of XPG expression in control (A) and phorbol ester-treated Jurkat (B) nuclear extracts.

XPG (G-4) - sc-393004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XPG (G-4): sc-393004. Western blot analysis of XPG expression in Jurkat nuclear extract.

XPG (E-18) - sc-12558 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XPG (E-18): sc-12558. Western blot analysis of XPG expression in phorbal ester-treated Jurkat nuclear extract.

XPG (P-19) - sc-84662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
XPG (P-19): sc-84662. Western blot analysis of XPG expression in non-transfected: sc-117752 (A) and human XPG transfected: sc-170683 (B) 293T whole cell lysates.

XPG (T-17) - sc-84663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
XPG (T-17): sc-84663. Western blot analysis of XPG expression in non-transfected: sc-117752 (A) and human XPG transfected: sc-170683 (B) 293T whole cell lysates.

XPG (3C189) - sc-73274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XPG (3C189): sc-73274. Western blot analysis of XPG expression in Jurkat nuclear extract.

Anti-XPG antibody - ab64931 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-XPG antibody (ab64931) at 1/500 dilutionLane 1 : Extracts from K562 cellsLane 2 : Extracts from K562 cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-XPG antibody - ab189317 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-XPG antibody (ab189317) at 1/500 dilutionLane 1 : COLO cell extractLane 2 : COLO cell extract with immunizing peptide

Anti-XPG antibody - ab99248 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Staining of XPG in a Formalin/PFA-fixed paraffin-embedded sections of Human Ovarian Carcinoma using ab99248 at a dilution of 1/250. Detection: DAB staining.

Anti-XPG antibody - ab62749 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-XPG antibody - ab171808 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-XPG antibody (ab171808) at 1/500 dilutionLane 1 : XPG transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-XPG antibody [8H7] - ab46 from Abcam

Prices $372.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 8H7

Anti-XPG antibody - C-terminal - ab173532 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-XPG antibody - C-terminal (ab173532) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-ERCC5 / XPG Antibody - LS-C26428 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-ERCC5 / XPG Antibody - LS-C124813 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ERCC5 / XPG Antibody (aa182-231) - LS-C81832 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.

Anti-ERCC5 / XPG Antibody (clone 2328C1a) - LS-C184665 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2328C1a

Anti-ERCC5 / XPG Antibody (Glu160) - LS-C191961 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ERCC5 / XPG Antibody (aa1151-1178) - LS-C159562 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ERCC5 Antibody western blot of CEM cell line lysates (35 ug/lane). The ERCC5 antibody detected the ERCC5 protein (arrow).

Anti-ERCC5 / XPG Antibody (aa1150-1178, AP) - LS-C256770 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ERCC5 / XPG Antibody - LS-C192764 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of fetal brain lysate, using ERCC5 antibody.

Anti-ERCC5 / XPG Antibody (aa131-180) IHC-plus™ - LS-B9142 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Prostate: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-ERCC5 / XPG Antibody (aa1150-1178, APC) - LS-C256771 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ERCC5 / XPG Antibody (aa1150-1178, Biotin) - LS-C256772 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ERCC5 / XPG Antibody (aa1150-1178, FITC) - LS-C256773 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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