ERCC5

Gene Symbol ERCC5
Entrez Gene 2073
Alt Symbol COFS3, ERCC5-201, ERCM2, UVDR, XPG, XPGC
Species Human
Gene Type protein-coding
Description excision repair cross-complementation group 5
Other Description DNA excision repair protein ERCC-5|DNA repair protein complementing XP-G cells|XPG-complementing protein|excision repair cross-complementing rodent repair deficiency, complementation group 5|xeroderma pigmentosum, complementation group G
Swissprots Q9HD60 Q9HD59 P28715 Q8N1B7 Q5JUS5 Q8IZL6 A6NGT4 Q7Z2V3 Q5JUS4
Accessions AAF89177 AAF89178 AAF89179 AAN46091 CAA50481 EAX09071 EAX09072 P28715 AF462447 AAP97715 AK294708 BAG57863 AK299758 BAG61647 AK303558 BAG64582 BC031522 AAH31522 BE223050 BQ002437 BQ707436 BX647399 D16305 BAA03812 DA195001 DQ891818 ABM82744 DQ895006 ABM85932 L20046 AAC37533 LM994821 CDY80174 X69978 CAA49598 NM_000123 NP_000114
Function Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Subcellular Location Nucleus {ECO:0000269|PubMed:7651464}.
Top Pathways Nucleotide excision repair

XPG CRISPR/Cas9 KO Plasmid (h) - sc-416940 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG HDR Plasmid (h) - sc-416940-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG Double Nickase Plasmid (h) - sc-416940-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG Double Nickase Plasmid (h2) - sc-416940-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG CRISPR Activation Plasmid (h) - sc-416940-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG CRISPR Activation Plasmid (h2) - sc-416940-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG Lentiviral Activation Particles (h) - sc-416940-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG Lentiviral Activation Particles (h2) - sc-416940-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPG siRNA (h) - sc-36857 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPG shRNA Plasmid (h) - sc-36857-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPG shRNA (h) Lentiviral Particles - sc-36857-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPG RNAi - H00002073-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU073531 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7952 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7952 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ERCC5 siRNA (Human) - CRH1448 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERCC5 - MBS8229344 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ERCC5 (NM_000123.3) - SHH286925 from Creative biogene

Category siRNA
Species Reactivities Human

Human ERCC5 siRNA - orb261950 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERCC5 shRNA Plasmid (Human) - CHH1448 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ERCC5 miRNA 3'UTR clone - MiUTR1H-03291 from Creative biogene

Species Reactivities Human
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