TNS3

Gene Symbol TNS3
Entrez Gene 64759
Alt Symbol TEM6, TENS1
Species Human
Gene Type protein-coding
Description tensin 3
Other Description tensin-3|tensin-like SH2 domain containing 1|tensin-like SH2 domain-containing 1|tensin-like SH2 domain-containing protein 1|thyroid specific PTB domain protein|tumor endothelial marker 6
Swissprots Q8NAD0 Q6IPQ2 B2RNV1 Q96S48 Q96PE0 Q8IZW7 Q68CZ2
Accessions AAQ96841 CBX47573 EAW61011 EAW61012 EAW61013 EAW61014 EAW61015 Q68CZ2 AB062750 BAB60681 AB208995 BAD92232 AF378756 AAL11993 AF417489 AAN32667 AK001539 AK002151 AK023794 BAB14682 AK092864 BAC03993 AK310472 AL833845 CAD38705 BC071791 AAH71791 BC137133 AAI37134 BC137134 AAI37135 BX648770 BX649002 CR749644 CAH18438 XM_011515476 XP_011513778 XM_011515477 XP_011513779 XM_011515478 XP_011513780 XM_011515479 XP_011513781 XM_011515480 XP_011513782 XM_011515481 XP_011513783 XM_011515482 XP_011513784 XM_011515483 XP_011513785 XM_011515484 XP_011513786 NM_022748 NP_073585
Function May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity). {ECO:0000250}.
Subcellular Location Cell junction, focal adhesion {ECO:0000269|PubMed:15140944, ECO:0000269|PubMed:17643115}.
Tissue Specificity Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial cells. Expression seems to be down-regulated in thyroid tumor tissues and in anaplastic carcinomas. {ECO:0000269|PubMed:11559528, ECO:0000269|PubMed:15140944, ECO:0000269|PubMed:16461921}.

Human TNS3 / Tensin 3 ELISA Kit (Sandwich ELISA) - LS-F8313 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 0.052 ng/ml
Range 0.156-10 ng/ml

Tensin 3 (TNS3), Human, ELISA Kit - SEF819Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.061ng/mL
Range 0.156-10ng/mL

Tensin 3, ELISA Kit - MBS072533 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tensin 3, ELISA Kit - MBS070780 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tensin 3, ELISA Kit - MBS093366 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tensin 3, ELISA Kit - MBS086712 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tensin 3, ELISA Kit - MBS105933 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tensin 3, ELISA Kit - MBS074202 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tensin 3 (TNS3), ELISA Kit - MBS2022933 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.052ng/mL.
Range 0.156-10ng/mL

Tensin 3, ELISA Kit - MBS097571 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Tensin 3 (TNS3) - SEF819Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.052ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Tensin 3 (TNS3) - SEF819Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.052ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Tensin 3 (TNS3) ELISA Kit - EKU07596 from Biomatik

Category ELISA Kit
Prices $735.00, $3,234.00, $5,880.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.052 ng/mL
Range 0.156-10 ng/mL

Human Tensin 3 ELISA Kit - abx153250 from Abbexa

Category ELISA Kit
Sensitivity 0.052 ng/ml
Range 0.156 ng/ml - 10 ng/ml

Tensin 3 (TNS3), Human, ELISA Kit - DL-TNS3-Hu from ARP American Research Products

Category ELISA Kit
Prices $655.00
Sizes 96 t
Range 0.156-10 ng/mL

Human TNS3 ELISA Kit - abx571385 from Abbexa

Category ELISA Kit
Sensitivity 0.061 ng/ml
Range 0.156 ng/ml - 10 ng/ml

Human TNS3 ELISA Kit - E037724 from Biobool

Category ELISA Kit

TNS3 ELISA Kit (Human) (OKCD00479) - OKCD00479 from Aviva Systems Biology

Category ELISA Kit
Prices $545.00
Sizes 96 wells
Sensitivity < 0.052 ng/mL
Range 0.156-10 ng/mL

TNS3 ELISA Kit (Human) (OKDD00570) - OKDD00570 from Aviva Systems Biology

Category ELISA Kit
Prices $580.00
Sizes 96 wells
Sensitivity < 0.061 ng/mL
Range 0.156-10 ng/mL

Human Tensin-3 (TNS3) ELISA Kit - AE13857HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t

Tensin 3 (TNS3), ELISA Kit - MBS454495 from MyBioSource

Category ELISA Kit
Prices $415.00, $550.00, $2,425.00, $4,710.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity <0.061ng/mL
Range 0.156-10ng/mL

Tensin 3 (TNS3), ELISA Kit - MBS9372402 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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