PF4

Gene Symbol PF4
Entrez Gene 5196
Alt Symbol CXCL4, PF-4, SCYB4
Species Human
Gene Type protein-coding
Description platelet factor 4
Other Description C-X-C motif chemokine 4|chemokine (C-X-C motif) ligand 4|iroplact|oncostatin-A
Swissprots Q9UC65 Q53X61 Q9UC64 P02776
Accessions AAK29643 AAY41003 EAX05694 P02776 AJ705588 BC093965 AAH93965 BC112093 AAI12094 CR407677 CAG28605 GD143506 M25897 AAA60066 XM_005265696 XP_005265753 NM_002619 NP_002610
Function Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. {ECO:0000269|PubMed:7644496}.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

PF-4 (D-7) - sc-398979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PF-4 (D-7): sc-398979. Western blot analysis of PF-4 expression in human spleen tissue extract (A) and human platelet extract (B).

PF-4 (G-7) - sc-374195 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PF-4 (G-7): sc-374195. Western blot analysis of PF-4 expression in human platelet extract.

PF-4 (PF63.1) - sc-73638 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PF-4 (PF63.1): sc-73638. Western blot analysis of PF-4 expression in human platelet extract.

PF-4 (H-40) - sc-50301 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PF-4 (H-40): sc-50301. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bone marrow tissue showing cytoplasmic staining of megakaryocytes and other hematopoietic cells.

PF-4 (V-15) - sc-23519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PF-4 (V-15): sc-23519. Western blot analysis of PF-4 expression in human platelet extract.

Anti-PF4 antibody - ab9561 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PF4 antibody (ab9561) at 1 µg/ml + Human Platelet (Human adult normal cell line) Whole Cell Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PF4 antibody - ab202957 from Abcam

Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded rat kidney tissue sections labeling PF4 with ab202957 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-PF4 antibody - ab64280 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PF4 antibody (ab64280) at 1 µg/ml + Human Platelet (Human adult normal cell line) Whole Cell Lysate at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PF4 antibody (Biotin) - ab83123 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PF4 antibody [EPR7762] - ab129090 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7762
All lanes : Anti-PF4 antibody [EPR7762] (ab129090) at 1/1000 dilutionLane 1 : Human spleen lysateLane 2 : Human platelet lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PF4 antibody [EPR7763] - ab129183 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7763
All lanes : Anti-PF4 antibody [EPR7763] (ab129183) at 1/1000 dilutionLane 1 : Human spleen lysatesLane 2 : Human platelet lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PF4 antibody [RTO] - ab49735 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone RTO
Anti-PF4 antibody [RTO] (ab49735) at 1 µg/ml + Human Platelet (Human adult normal cell line) Whole Cell Lysate at 20 µgSecondaryGoat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PF4 antibody [RTO] (Biotin) - ab112229 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone RTO

Anti-PF4 antibody [RTO] - BSA and Azide free - ab174795 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone RTO

Anti-CXCL4 / PF4 Antibody (HRP) - LS-C9572 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CXCL4 / PF4 Antibody - LS-C9573 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CXCL4 / PF4 Antibody (PE) - LS-C38159 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CXCL4 / PF4 Antibody (CF) - LS-C38158 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CXCL4 / PF4 Antibody - LS-C147791 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXCL4 / PF4 Antibody (HRP) - LS-C193855 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CXCL4 / PF4 Antibody - LS-C193662 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CXCL4 / PF4 Antibody (aa30-105) - LS-C295962 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXCL4 / PF4 Antibody (Internal, clone EPR7762) - LS-C152500 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone EPR7762
Western blot analysis on (A) human spleen and (B) human platelet lysates using anti-PF4 antibody.

Anti-CXCL4 / PF4 Antibody (aa31-101, Biotin) - LS-C299044 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CXCL4 / PF4 Antibody (aa30-105, Biotin) - LS-C299045 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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