PF4

Gene Symbol PF4
Entrez Gene 5196
Alt Symbol CXCL4, PF-4, SCYB4
Species Human
Gene Type protein-coding
Description platelet factor 4
Other Description C-X-C motif chemokine 4|chemokine (C-X-C motif) ligand 4|iroplact|oncostatin-A
Swissprots Q9UC65 Q53X61 Q9UC64 P02776
Accessions AAK29643 AAY41003 EAX05694 P02776 AJ705588 BC093965 AAH93965 BC112093 AAI12094 CR407677 CAG28605 GD143506 M25897 AAA60066 XM_005265696 XP_005265753 NM_002619 NP_002610
Function Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. {ECO:0000269|PubMed:7644496}.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

PF4-Over-expression-Lysate - LY10570a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PF4 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PF4 gene (Lane 2, Cat. #LY10570a).

PF4 overexpression lysate - LY400930 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

PF4 293 Cell Lysate - 400875 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CXCL4/PF4 Overexpression Lysate (Native) - NBL1-14305 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: PF4/Platelet factor 4 Overexpression Lysate (Adult Normal) [NBL1-14305] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PF4/Platelet factor 4.

PF4 Over-expression Lysate Product - GWB-212C3B from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

CXCL4/PF4 Overexpression Lysate (Denatured) - H00005196-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human PF4 Knockdown Stable Cell Line - CSC-DC011616 from Creative biogene

Category Cell Line
Species Human
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