PF4

Gene Symbol PF4
Entrez Gene 5196
Alt Symbol CXCL4, PF-4, SCYB4
Species Human
Gene Type protein-coding
Description platelet factor 4
Other Description C-X-C motif chemokine 4|chemokine (C-X-C motif) ligand 4|iroplact|oncostatin-A
Swissprots Q9UC65 Q53X61 Q9UC64 P02776
Accessions AAK29643 AAY41003 EAX05694 P02776 AJ705588 BC093965 AAH93965 BC112093 AAI12094 CR407677 CAG28605 GD143506 M25897 AAA60066 XM_005265696 XP_005265753 NM_002619 NP_002610
Function Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. {ECO:0000269|PubMed:7644496}.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

PF-4 CRISPR/Cas9 KO Plasmid (h) - sc-417036 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 HDR Plasmid (h) - sc-417036-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 Double Nickase Plasmid (h) - sc-417036-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 Double Nickase Plasmid (h2) - sc-417036-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 CRISPR Activation Plasmid (h) - sc-417036-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 CRISPR Activation Plasmid (h2) - sc-417036-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 Lentiviral Activation Particles (h) - sc-417036-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 Lentiviral Activation Particles (h2) - sc-417036-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PF-4 siRNA (h) - sc-39364 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PF-4 shRNA Plasmid (h) - sc-39364-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PF-4 shRNA (h) Lentiviral Particles - sc-39364-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU112751 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16646 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16646 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PF4 siRNA (Human) - CRH3468 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CXCL4/PF4 RNAi - H00005196-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PF4 (NM_002619.3) - SHH373828 from Creative biogene

Category siRNA
Species Reactivities Human

Human PF4 siRNA - orb263970 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PF4 shRNA Plasmid (Human) - CHH3468 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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