PDE1B

Gene Symbol PDE1B
Entrez Gene 5153
Alt Symbol PDE1B1, PDES1B
Species Human
Gene Type protein-coding
Description phosphodiesterase 1B, calmodulin-dependent
Other Description 63 kDa Cam-PDE|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B|calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase|calmodulin-stimulated phosphodiesterase PDE1B1|cam-PDE 1B|presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
Swissprots Q92825 Q96KP3 Q01064
Accessions AAC51871 EAW96788 EAW96789 EAW96790 EAW96791 Q01064 AB209200 BAD92437 AJ401609 CAC82207 AK126899 BAG54390 AK296422 BAG59084 AK302899 BAG64072 AK302931 BAG64092 BC032226 AAH32226 BP342896 BX538092 CAD98011 DA254686 DC298452 DC392024 DQ891673 ABM82599 DQ894859 ABM85785 EU668337 ACF94490 M94539 AAA58405 U40584 AAB50018 U56976 AAC50769 U86078 AAC51872 XM_006719451 XP_006719514 XM_011538456 XP_011536758 NM_000924 NP_000915 NM_001165975 NP_001159447 NM_001288768 NP_001275697 NM_001288769 NP_001275698
Function Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. {ECO:0000269|PubMed:15260978}.
Subcellular Location Cytoplasm.
Top Pathways Calcium signaling pathway, Morphine addiction, Purine metabolism

PDE1B (G-5) - sc-393112 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE1B (G-5): sc-393112. Western blot analysis of PDE1B expression in mouse brain (A) and human hippocampus (B) tissue extracts.

PDE1B (N-18) - sc-23071 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE1B (N-18): sc-23071. Western blot analysis of PDE1B expression in mouse brain tissue extract.

PDE1B (D-11) - sc-393349 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE1B (D-11): sc-393349. Western blot analysis of PDE1B expression in mouse brain tissue extract.

Anti-PDE1B antibody - ab14600 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE1B antibody - ab129555 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PDE1B antibody (ab129555) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

Anti-PDE1B antibody - ab55564 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55564 PDE1B antibody at 1ug/ml.

Anti-PDE1B antibody [EPR12293(2)] - ab182565 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12293(2)
Immunohistochemical analysis of paraffin-embedded Human cerebellum tissue labeling PDE1B with ab182565 at 1/100 dilution followed by prediluted HRP Polymer for Rabbit IgG. Counter stained with Hematoxylin.

Anti-PDE1B antibody - C-terminal - ab170441 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling PDE1B with ab170441 at 1/10 dilution, followed by a peroxidase conjugated secondary antibody and DAB staining.

Anti-PDE1B Antibody (C-Terminus) - LS-C112315 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDE1B antibody LS-C112315 Western blot of HT1080 Cell lysate. Antibody concentration 1 ug/ml.

Anti-PDE1B Antibody (aa467-495) - LS-C163468 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PDE1B Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The PDE1B antibody detected the PDE1B protein (arrow).

Anti-PDE1B Antibody (aa473-500, AP) - LS-C265863 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa473-500, APC) - LS-C265864 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa473-500, Biotin) - LS-C265865 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa473-500, FITC) - LS-C265866 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa473-500, Azide-free, HRP) - LS-C265867 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody - LS-C192857 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of various cell lines, using PDE1B antibody.

Anti-PDE1B Antibody (clone 1D6) - LS-C173200 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D6
Anti-PDE1B mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE1B.

Anti-PDE1B Antibody (aa473-500) - LS-C163467 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PDE1B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PDE1B Antibody (aa473-500, PE) - LS-C265868 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (clone 5B6) - LS-C197863 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B6
Detection limit for recombinant GST tagged PDE1B is approximately 0.03 ng/ml as a capture antibody.

Anti-PDE1B Antibody (aa467-495, AP) - LS-C265869 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa467-495, APC) - LS-C265870 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa467-495, Biotin) - LS-C265871 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa467-495, FITC) - LS-C265872 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1B Antibody (aa467-495, Azide-free, HRP) - LS-C265873 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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