| Gene Symbol |
PDE1B
|
| Entrez Gene |
5153
|
| Alt Symbol |
PDE1B1, PDES1B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphodiesterase 1B, calmodulin-dependent
|
| Other Description |
63 kDa Cam-PDE|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B|calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase|calmodulin-stimulated phosphodiesterase PDE1B1|cam-PDE 1B|presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
|
| Swissprots |
Q92825 Q96KP3 Q01064
|
| Accessions |
AAC51871 EAW96788 EAW96789 EAW96790 EAW96791 Q01064 AB209200 BAD92437 AJ401609 CAC82207 AK126899 BAG54390 AK296422 BAG59084 AK302899 BAG64072 AK302931 BAG64092 BC032226 AAH32226 BP342896 BX538092 CAD98011 DA254686 DC298452 DC392024 DQ891673 ABM82599 DQ894859 ABM85785 EU668337 ACF94490 M94539 AAA58405 U40584 AAB50018 U56976 AAC50769 U86078 AAC51872 XM_006719451 XP_006719514 XM_011538456 XP_011536758 NM_000924 NP_000915 NM_001165975 NP_001159447 NM_001288768 NP_001275697 NM_001288769 NP_001275698
|
| Function |
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. {ECO:0000269|PubMed:15260978}.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Calcium signaling pathway, Morphine addiction, Purine metabolism
|
![Western Blot: PDE1B Overexpression Lysate (Adult Normal) [NBL1-14215] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PDE1B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9817_PDE1B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14215-img0002.jpg)