Gene Symbol | RIN2 |
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Entrez Gene | 54453 |
Alt Symbol | MACS, RASSF4 |
Species | Human |
Gene Type | protein-coding |
Description | Ras and Rab interactor 2 |
Other Description | RAB5 interacting protein 2|RAS association (RalGDS/AF-6) domain containing protein JC265|RAS association domain family 4|RAS inhibitor JC265|RAS interaction/interference protein 2|ras and Rab interactor 2 |
Swissprots | Q9H071 Q00425 Q5TFT8 Q9BQL3 Q8WYP3 |
Accessions | EAX10216 EAX10217 Q8WYP3 AB060339 BAB84317 AI695804 AK026753 AK094884 BAG52947 AL136924 CAB66858 BC034698 BC090059 BC128065 AAI28066 BM973182 HG511229 HG511230 HG511231 M37190 AAA36553 XM_005260731 XP_005260788 XM_005260732 XP_005260789 XM_005260733 XP_005260790 XM_006723574 XP_006723637 XM_006723575 XP_006723638 XM_006723577 XP_006723640 XM_011529255 XP_011527557 XM_011529256 XP_011527558 XM_011529257 XP_011527559 XM_011529258 XP_011527560 XM_011529259 XP_011527561 XM_011529260 XP_011527562 NM_001242581 NP_001229510 NM_018993 NP_061866 |
Function | Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP. {ECO:0000269|PubMed:11733506}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Tissue Specificity | Widely expressed. Expressed in heart, kidney, lung placenta. Expressed at low level in skeletal muscle, spleen and peripheral blood. {ECO:0000269|PubMed:11733506}. |
RIN2 (E-20) - sc-85888 from Santa Cruz Biotechnology
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RIN2 (F-16) - sc-85889 from Santa Cruz Biotechnology
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RIN2 (N-17) - sc-85890 from Santa Cruz Biotechnology
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Anti-RIN2 antibody - ab57377 from Abcam
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Anti-RIN2 antibody - ab127042 from Abcam
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Anti-MACS / RIN2 Antibody (aa37-86) - LS-C186791 from LifeSpan Bioscience
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Anti-MACS / RIN2 Antibody (clone 1E7) - LS-C105149 from LifeSpan Bioscience
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RIN2 Antibody - NBP2-20163 from Novus Biologicals
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RIN2 Antibody - NBP1-80854 from Novus Biologicals
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RIN2 Antibody (1E7) - H00054453-M01 from Novus Biologicals
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RIN2 Antibody (1E6) - H00054453-M04 from Novus Biologicals
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RIN2 Antibody - H00054453-A01 from Novus Biologicals
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Monoclonal Anti-RIN2 antibody produced in mouse - WH0054453M1 from Sigma-Aldrich
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Anti-RIN2 antibody produced in rabbit - HPA034641 from Sigma-Aldrich
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RIN2 Antibody - N-terminal region (ARP66262_P050) - ARP66262_P050 from Aviva Systems Biology
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RIN2-Antibody-monoclonal-M04 - AT3643a from Abgent, a WuXi AppTec company
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RIN2-Antibody-monoclonal-M01 - AT3642a from Abgent, a WuXi AppTec company
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RIN2 antibody - H00054453-A01 from Acris Antibodies
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RIN2 antibody - H00054453-M01 from Acris Antibodies
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RIN2 antibody - H00054453-M04 from Acris Antibodies
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Anti-RIN2 (aa 786-894) polyclonal antibody - DPAB-DC2325 from Creative Diagnostics
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Anti-RIN2 (aa 6-245) polyclonal antibody - DPABH-23119 from Creative Diagnostics
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RIN2 Polyclonal Antibody - PA5-30882 from Thermo Fisher Scientific
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RIN2 - MBS274969 from MyBioSource
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Anti-Ras and Rab interactor 2 - 08A054453 from MP Biomedicals
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